Medical Faculty in Katowice, Department of Pathophysiology, Pathophysiology Unit, The Medical University of Silesia, Katowice, Poland.
International Institute of Molecular and Cell Biology, Warsaw, Poland.
PLoS One. 2022 Aug 22;17(8):e0272045. doi: 10.1371/journal.pone.0272045. eCollection 2022.
To determine the prevalence of treated and untreated thyroid dysfunction and to identify factors associated with increased risk of undiagnosed thyroid dysfunction in older adults.
The population of 5987 community-dwelling Polish Caucasian seniors aged 60 years and above who participated in the PolSenior 2 study (2018-2019). Population-based cross-sectional multidisciplinary study in design. Data from structured questionnaires, geriatric tests, and scales were obtained from all study participants who underwent anthropometric and blood pressure measurements during three home visits. Assessment of thyroid function was based on TSH serum measurements.
The prevalence of thyroid dysfunction in the Polish population aged 60 years or above was estimated at 15.5% (21.5% in women and 7.2% in men), with 3.2% of undiagnosed individuals among them. The prevalence of hypothyroidism and hyperthyroidism in the studied group was 13.9% (19.4% in women and 6.3% in men) and 1.6% (2.1% in women and 0.9% in men) respectively, untreated hypothyroidism was revealed in 21.9% (in 160 out of 732 subjects) and untreated hyperthyroidism in 34.2% of subjects (in 41 out of 120 participants). In multiple regression analysis independent risk factors for thyroid disorders being untreated were older age (> 75 years), male sex, a low education level (primary or lower), and low utilization of medical services.
One-fifth of Polish Caucasian seniors with hypothyroidism and one-third with hyperthyroidism are untreated. Older, poorly educated and rarely utilizing medical services seniors, especially men, are more frequently untreated for thyroid dysfunction and some of them do not benefit from contemporary achievements in medicine.
目的是确定治疗和未治疗的甲状腺功能障碍的患病率,并确定与老年人未确诊甲状腺功能障碍风险增加相关的因素。
研究对象为参与 PolSenior 2 研究(2018-2019 年)的 5987 名年龄在 60 岁及以上的居住在社区的波兰白种老年人。这是一项基于人群的、横断面的多学科研究。所有研究参与者在三次家访期间接受了体格检查、老年测试和量表的评估,研究人员从他们那里获得了结构化问卷、人口统计学和血压测量数据。甲状腺功能的评估基于 TSH 血清测量值。
波兰 60 岁及以上人群的甲状腺功能障碍患病率估计为 15.5%(女性为 21.5%,男性为 7.2%),其中 3.2%为未确诊的患者。在研究组中,甲状腺功能减退症和甲状腺功能亢进症的患病率分别为 13.9%(女性为 19.4%,男性为 6.3%)和 1.6%(女性为 2.1%,男性为 0.9%),未治疗的甲状腺功能减退症在 21.9%(732 名受试者中有 160 名),未治疗的甲状腺功能亢进症在 34.2%(120 名参与者中有 41 名)。在多因素回归分析中,甲状腺疾病未得到治疗的独立危险因素为年龄较大(>75 岁)、男性、教育程度较低(小学及以下)和医疗服务利用率较低。
波兰白种老年人中五分之一的甲状腺功能减退症和三分之一的甲状腺功能亢进症未得到治疗。年龄较大、教育程度较低、很少利用医疗服务的老年人,尤其是男性,未治疗的甲状腺功能障碍更为常见,他们中的一些人无法从当代医学的成就中受益。