Pizzorno Lara, Pizzorno Joseph
Integr Med (Encinitas). 2022 Jul;21(3):8-15.
While Cushing syndrome is rare, but well-recognized, subclinical hypercortisolism (defined as excessive cortisol secretion without the classic manifestations of Cushing syndrome) is significantly more common. Subclinical hypercortisolism contributes to several chronic diseases, such as diabetes, osteoporosis, sarcopenia and hypertension. The incidence increases with age and correlates with body load of environmental toxins such as bisphenol A (BPA). This editorial discusses prevalence, contribution to disease, causes, diagnosis, and intervention.
虽然库欣综合征罕见,但广为人知,而亚临床皮质醇增多症(定义为皮质醇分泌过多但无库欣综合征的典型表现)则更为常见。亚临床皮质醇增多症会引发多种慢性疾病,如糖尿病、骨质疏松症、肌肉减少症和高血压。其发病率随年龄增长而增加,且与双酚A(BPA)等环境毒素的身体负荷相关。本社论讨论了其患病率、对疾病的影响、病因、诊断和干预措施。