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[我的舌头在灼痛!——舌痛症/口面部疼痛障碍]

[My tongue is burning!-Glossodynia/orofacial pain disorder].

作者信息

Gieler U, Gieler T, Steinhoff M

机构信息

Universitäts-Hautklinik Gießen, Vitos Klinik für Psychosomatik Gießen, Licher Str. 106, 35394, Gießen, Deutschland.

Universitäts-Kinderklinik Gießen - Kinder- und Jugendpsychosomatik, Gießen, Deutschland.

出版信息

Dermatologie (Heidelb). 2022 Sep;73(9):701-707. doi: 10.1007/s00105-022-05037-x. Epub 2022 Aug 23.

Abstract

Glossodynia or orofacial pain disorder is known as burning mouth syndrome. It is a therapeutic challenge. Its etiology is not well defined. Recent studies show not only a correlation with neuropathic changes, but there are also indications of comorbidities such as depression, anxiety, and carcinophobia. These can also manifest as a reaction to the disease and are not necessarily considered causative. Burning mouth syndrome poses a diagnostic challenge since its differential diagnosis is broad. With regard to dermatological aspects, lichen planus mucosae, oral leucoplakia, pemphigus vulgaris, and aphthous mouth ulcers should be considered. Diabetes, anemia, vitamin deficiency, and endocrinological influences should be considered regarding the predominance of elderly and female patients. Meta-analyses of treatment studies usually show a low level of evidence of the randomized, controlled trials. According to the literature mainly psychotherapy and antidepressants are proposed for therapy. Alpha lipoic acid as a dietary supplement shows short-term improvement and low-level laser therapy might have some benefit.

摘要

舌痛症或口面部疼痛障碍被称为灼口综合征。这是一个治疗难题。其病因尚不明确。最近的研究表明,它不仅与神经病变有关,而且还有诸如抑郁、焦虑和恐癌等合并症的迹象。这些也可能表现为对疾病的反应,不一定被视为病因。灼口综合征的鉴别诊断范围广泛,因此在诊断上具有挑战性。在皮肤病学方面,应考虑黏膜扁平苔藓、口腔白斑、寻常型天疱疮和复发性口腔溃疡。鉴于老年女性患者占多数,应考虑糖尿病、贫血、维生素缺乏和内分泌影响。治疗研究的荟萃分析通常显示随机对照试验的证据水平较低。根据文献,主要建议采用心理治疗和抗抑郁药进行治疗。作为膳食补充剂的α硫辛酸显示出短期改善,低强度激光治疗可能有一定益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1554/9396595/03c5a27738b8/105_2022_5037_Fig1_HTML.jpg

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