Shan Xiao, Qian Maolin, Wang Lan, Liu Xiaoqin
Medical School of Nantong University, Nantong, 226000, Jiangsu, China.
Department of outpatient, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Int Urogynecol J. 2023 Mar;34(3):655-664. doi: 10.1007/s00192-022-05326-y. Epub 2022 Aug 24.
Pelvic floor dysfunction (PFD) and female sexual dysfunction (FSD) are symptoms that affect the quality of life of patients with cervical cancer (CC) after treatment. Our purpose was to estimate the prevalence of urinary incontinence (UI) and fecal incontinence (FI) associated with PFD and prevalence of FSD in CC patients.
We searched PubMed, Embase, and the Cochrane Library from database inception to 31 January 2021 and selected articles assessing UI, FI and FSD in women with CC. Observational studies were included if they investigated UI, FI, and FSD.
We included 14 of the 1,233 studies: 7 investigated FSD, 9 UI, and 3 FI. The results were highly heterogeneous because of the different populations and treatment methods. The prevalence of FSD, UI, and FI in CC patients after treatment was 45.0% (95% CI, 21.8-68.3%), 34.1% (95% CI, 25.5-42.7%), and 11.1% (95% CI, 4.8-17.3%). The results showed that different countries were the source of high heterogeneity of UI and FI (P<0.001).
In this meta-analysis, the prevalence of PFD and FSD was high. These results are important for drawing attention to PFD and its early prevention and rehabilitation.
盆底功能障碍（PFD）和女性性功能障碍（FSD）是影响宫颈癌（CC）患者治疗后生活质量的症状。我们的目的是评估与PFD相关的尿失禁（UI）和粪失禁（FI）的患病率以及CC患者中FSD的患病率。
我们检索了从数据库建立至2021年1月31日的PubMed、Embase和Cochrane图书馆，并选择了评估CC女性患者UI、FI和FSD的文章。如果观察性研究调查了UI、FI和FSD，则将其纳入。
我们从1233项研究中纳入了14项：7项研究FSD，9项研究UI，3项研究FI。由于人群和治疗方法不同，结果具有高度异质性。CC患者治疗后FSD、UI和FI的患病率分别为45.0%（95%CI，21.8 - 68.3%）、34.1%（95%CI，25.5 - 42.7%）和11.1%（95%CI，4.8 - 17.3%）。结果表明，不同国家是UI和FI高度异质性的来源（P<0.001）。
在这项荟萃分析中，PFD和FSD的患病率较高。这些结果对于引起对PFD及其早期预防和康复的关注具有重要意义。
