Division of Speech and Hearing Sciences, Department of Allied Health Sciences, University of North Carolina at Chapel Hill.
Department of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill.
J Speech Lang Hear Res. 2022 Sep 12;65(9):3539-3547. doi: 10.1044/2022_JSLHR-22-00039. Epub 2022 Aug 24.
The U.S. Food and Drug Administration indications for cochlear implantation in children is currently 9 months of age and older for children with bilateral profound sensorineural hearing loss (SNHL). Studies have shown that earlier activation of a cochlear implant (CI) can lead to better spoken language outcomes. As auditory skills are a precursor to the development of spoken language, this study was developed to investigate the influence of age at CI activation on auditory skill acquisition in young children. A secondary aim was to describe the auditory skills of children implanted prior to 9 months of age as compared to children with older ages of activation.
Functional Listening Index (FLI) scores obtained during routine clinical visits were reviewed for 78 pediatric CI recipients with congenital bilateral profound hearing loss who were activated before 2 years of age. A linear mixed-effects model assessed the effect of age at CI activation on cumulative FLI scores over time.
There was a significant interaction between age at activation and chronological age at the time of evaluation, indicating that children with earlier access to sound achieved a greater number of auditory skills than those with later CI activations when measured at the same chronological age. Children activated before the age of 9 months approximated scores expected of children with typical hearing, whereas children activated between 9 and 24 months of age did not.
Younger age at CI activation is associated with increased auditory skills over time. Children who undergo cochlear implantation and CI activation before 9 months achieve more auditory skills by 4 years of age than children who are activated at later ages. These data suggest that reducing the approved age at cochlear implantation for children with congenital bilateral profound SNHL may support optimal auditory skill acquisition.
美国食品和药物管理局(FDA)目前批准的儿童耳蜗植入适应证为双侧极重度感音神经性听力损失(SNHL)患儿年龄≥9 个月。研究表明,耳蜗植入(CI)更早激活可带来更好的言语语言结局。由于听觉技能是言语语言发展的前提,本研究旨在探讨 CI 激活年龄对婴幼儿听觉技能习得的影响。次要目的是比较 9 个月龄前和大龄儿童的听觉技能,描述植入 CI 前年龄较小的儿童的听觉技能。
回顾了 78 例先天性双侧极重度听力损失、2 岁前激活的儿童 CI 接受者在常规临床就诊期间获得的功能性聆听指数(FLI)评分。线性混合效应模型评估了 CI 激活年龄对随时间累积 FLI 评分的影响。
CI 激活年龄与评估时的实际年龄之间存在显著的交互作用,表明当以相同的实际年龄进行测量时,更早获得声音的儿童比较晚激活 CI 的儿童获得更多的听觉技能。9 个月龄前激活的儿童接近正常听力儿童的预期得分,而 9-24 个月龄激活的儿童则未达到。
CI 激活年龄越早,随时间推移听觉技能增加越多。在 9 个月龄前接受 CI 植入和激活的儿童,在 4 岁时获得的听觉技能比在较晚年龄激活的儿童更多。这些数据表明,降低先天性双侧极重度 SNHL 儿童耳蜗植入的批准年龄可能有助于支持最佳听觉技能习得。