Chweya Cynthia M, May Matthew M, DeJong Melissa D, Baas Becky S, Lohse Christine M, Driscoll Colin L W, Carlson Matthew L
Mayo Clinic Alix School of Medicine.
Department of Otolaryngology-Head and Neck Surgery.
Otol Neurotol. 2021 Jun 1;42(5):686-693. doi: 10.1097/MAO.0000000000003011.
To compare language and audiological outcomes among infants (<9 and <12 mo) and older children receiving cochlear implantation (CI).
Retrospective chart review.
Tertiary academic referral center.
Pediatric patients receiving CI between October 1995 and October 2019.
Cochlear implantation.
Most recent language and audiological assessment scores were evaluated by age group.
A total of 118 children were studied, including 19 who were implanted <9 months of age, 19 implanted 9 to <12 months of age, and 80 implanted 12 to <36 months of age. The mean duration of follow-up was 7.4 ± 5.0 years. Most recent REEL-3 receptive (88 ± 12 vs. 73 ± 15; p = 0.020) and expressive (95 ± 13 vs. 79 ± 12; p = 0.013) communication scores were significantly higher in the <9 months group compared to the 9 to <12 months group. PLS and OWLS auditory comprehension and oral expression scores were significantly higher in the <12 months group compared to the 12 to <36 months group. The difference in NU-CHIPS scores between <12 and 12 to <36 months was statistically significant (89% ± 6 vs. 83% ± 12; p = 0.009). LNT scores differed significantly between <9 and 9 to <12 months (94% ± 4 vs. 86% ± 10; p = 0.028).
The recent FDA expansion of pediatric CI eligibility criteria to include infants as young as 9 months of age should not serve as a strict clinical cutoff. Rather, CI can be pursued in appropriately selected younger infants to optimize language and audiological outcomes.
比较接受人工耳蜗植入(CI)的婴儿(<9个月和<12个月)与大龄儿童的语言和听力学结果。
回顾性病历审查。
三级学术转诊中心。
1995年10月至2019年10月期间接受CI的儿科患者。
人工耳蜗植入。
按年龄组评估最近的语言和听力学评估分数。
共研究了118名儿童,其中19名在9个月龄前植入,19名在9至<12个月龄植入,80名在12至<36个月龄植入。平均随访时间为7.4±5.0年。与9至<12个月组相比,<9个月组最近的REEL-3接受性(88±12对73±15;p=0.020)和表达性(95±13对79±12;p=0.013)沟通分数显著更高。与12至<36个月组相比,<12个月组的PLS和OWLS听觉理解及口语表达分数显著更高。<12个月组与12至<36个月组之间的NU-CHIPS分数差异具有统计学意义(89%±6对83%±12;p=0.009)。<9个月组与9至<12个月组之间的LNT分数差异显著(94%±4对86%±10;p=0.028)。
美国食品药品监督管理局(FDA)最近将儿科CI资格标准扩大到包括9个月龄的婴儿,这不应该作为严格的临床界限。相反,对于经过适当选择的更小婴儿,可以进行CI以优化语言和听力学结果。