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胎儿磁共振成像在脊髓神经管缺陷诊断中的应用:一项前瞻性研究。

Fetal magnetic resonance imaging in the diagnosis of spinal cord neural tube defects: A prospective study.

作者信息

Gao Gan, Tao Benzhang, Chen Yanyan, Yang Jiaqi, Sun Mengchun, Wang Hui, Hao Fangbin, Liu Simeng, Wang Minjie, Shang Aijia

机构信息

Department of Neurosurgery, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.

Chinese People's Liberation Army (PLA) Medical School, Beijing, China.

出版信息

Front Neurol. 2022 Aug 8;13:944666. doi: 10.3389/fneur.2022.944666. eCollection 2022.

Abstract

OBJECTIVE

This study aimed to evaluate the value of fetal magnetic resonance imaging (MRI) in the prenatal diagnosis of spinal neural tube defects.

METHODS

From August 2018 to January 2021, 56 fetuses with suspected spinal cord neural tube defects were treated by prenatal ultrasound in the Neurosurgery Department of the First Medical Center of the People's Liberation Army General Hospital. Fetal MRI was performed within 72 h after ultrasound diagnosis. Forty singleton fetuses were selected. Magnetic resonance examination was performed within 1 month after birth, and the diagnostic coincidence rates of prenatal ultrasound and fetal magnetic resonance examination in the prenatal diagnosis of spinal cord neural tube defects were compared and analyzed using postnatal magnetic resonance examination as the standard.

RESULTS

The coincidence rates of prenatal ultrasound and fetal MRI for the prenatal diagnosis of spina bifida were 71.4% (20/28) and 39.2% (11/28), respectively, and the difference was statistically significant. The coincidence rates of prenatal ultrasound and fetal MRI in the diagnosis of intraspinal lipoma were 52.6% (10/19) and 73.7% (14/19), respectively, and the difference was statistically significant.

CONCLUSION

Fetal MRI has an advantage over prenatal ultrasound in detecting intraspinal lipoma. Prenatal ultrasound has an advantage over fetal MRI in detecting spina bifida.

摘要

目的

本研究旨在评估胎儿磁共振成像(MRI)在脊髓神经管缺陷产前诊断中的价值。

方法

2018年8月至2021年1月,解放军总医院第一医学中心神经外科对56例疑似脊髓神经管缺陷的胎儿进行产前超声检查。在超声诊断后72小时内进行胎儿MRI检查。选取40例单胎胎儿。出生后1个月内进行磁共振检查,以出生后磁共振检查为标准,比较分析产前超声和胎儿磁共振检查在脊髓神经管缺陷产前诊断中的诊断符合率。

结果

产前超声和胎儿MRI对脊柱裂产前诊断的符合率分别为71.4%(20/28)和39.2%(11/28),差异有统计学意义。产前超声和胎儿MRI对脊髓内脂肪瘤诊断的符合率分别为52.6%(10/19)和73.7%(14/19),差异有统计学意义。

结论

胎儿MRI在检测脊髓内脂肪瘤方面优于产前超声。产前超声在检测脊柱裂方面优于胎儿MRI。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773a/9393549/5075e17443f2/fneur-13-944666-g0001.jpg

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