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俄罗斯成年人群中Ross手术术后的生存情况及再次手术的自由度:一项单中心经验。

Survival and freedom from reoperation after the Ross procedure in a Russian adult population: A single-center experience.

作者信息

Tsaroev Bashir, Chernov Igor, Enginoev Soslan, Mustaev Muslim

机构信息

Federal State Budgetary Institution "Federal Center for Cardiovascular Surgery" of the Ministry of Health of the Russian Federation, Astrakhan, Astrakhan Region, Russia.

Department of Vascular Surgery, Alexandro-Mariinsky Regional Clinical Hospital, Astrakhan, Astrakhan Region, Russia.

出版信息

JTCVS Open. 2022 Apr 21;10:140-147. doi: 10.1016/j.xjon.2022.04.026. eCollection 2022 Jun.

DOI:10.1016/j.xjon.2022.04.026
PMID:36004253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9390578/
Abstract

OBJECTIVES

To evaluate our 12-year experience with the Ross procedure in adults.

METHODS

A retrospective analysis of 215 cases of the Ross procedure was performed. The mean age of the patients was 36 ± 11.1 years, and the male to female ratio was 75% to 25%, respectively. The pulmonary autograft was placed into the aortic position using the full-root replacement technique and its modified versions. The right ventricular outflow tract was reconstructed using a pulmonary homograft in all cases.

RESULTS

The 30-day mortality after the operation was 0.9% (2 patients). The median duration of follow-up was 6.1 years (interquartile range, 6.5 years) and was complete in 86% of cases. The survival at 12 years was 94.7% and was comparable with the survival rate of the general population matched for age and sex. At the end of the follow-up, freedom from reoperation due to pulmonary autograft and homograft dysfunction was 89.1% and 99%, respectively.

CONCLUSIONS

In our series, the Ross procedure resulted in low early mortality and excellent survival in adults. The long-term survival was not statistically different from the survival of the general population. The pulmonary homograft offered an excellent durability and freedom from reoperation.

摘要

目的

评估我们在成人中开展罗斯手术的12年经验。

方法

对215例罗斯手术病例进行回顾性分析。患者的平均年龄为36±11.1岁,男女比例分别为75%和25%。采用全根置换技术及其改良术式将自体肺动脉瓣置于主动脉位置。所有病例均使用同种异体肺动脉瓣重建右心室流出道。

结果

术后30天死亡率为0.9%(2例患者)。随访的中位时间为6.1年(四分位间距为6.5年),86%的病例随访完整。12年生存率为94.7%,与年龄和性别匹配的普通人群生存率相当。随访结束时,因自体肺动脉瓣和同种异体肺动脉瓣功能障碍而再次手术的免再手术率分别为89.1%和99%。

结论

在我们的系列研究中,罗斯手术在成人中导致较低的早期死亡率和良好的生存率。长期生存率与普通人群的生存率无统计学差异。同种异体肺动脉瓣具有出色的耐久性和免再手术率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/4e24965b2050/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/56e9d7d0e6e5/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/34ccb8fd42ab/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/542b0c4f8e0a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/66976429bfdf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/84265cd02279/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/4e24965b2050/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/56e9d7d0e6e5/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/34ccb8fd42ab/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/542b0c4f8e0a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/66976429bfdf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/84265cd02279/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc44/9390578/4e24965b2050/gr4.jpg

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本文引用的文献

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Contemporary Ross procedure outcomes: medium- to long-term results in 214 patients.当代 Ross 手术结果:214 例患者的中-长期结果。
Eur J Cardiothorac Surg. 2021 Nov 2;60(5):1112-1121. doi: 10.1093/ejcts/ezab193.
2
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2020美国心脏病学会/美国心脏协会瓣膜性心脏病患者管理指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
Circulation. 2021 Feb 2;143(5):e72-e227. doi: 10.1161/CIR.0000000000000923. Epub 2020 Dec 17.
3
Outcome of 40 consecutive cases of modified Ross procedure using novel Dacron valved conduit.
连续40例使用新型涤纶带瓣管道的改良Ross手术的结果。
Indian J Thorac Cardiovasc Surg. 2020 Jan;36(1):28-36. doi: 10.1007/s12055-019-00845-8. Epub 2019 Jul 23.
4
The long term results of the Ross procedure: The importance of candidate selection.罗斯手术的长期结果:候选者选择的重要性。
Int J Cardiol. 2020 Dec 1;320:35-41. doi: 10.1016/j.ijcard.2020.07.009. Epub 2020 Jul 15.
5
A review of pulmonary autograft external support in the Ross procedure.Ross 手术中肺动脉体外支持的综述。
Expert Rev Med Devices. 2019 Nov;16(11):981-988. doi: 10.1080/17434440.2019.1685380. Epub 2019 Oct 31.
6
Long-term assessment of the Ross procedure in adults: Clinical and echocardiographic follow-up at 20 years.成人Ross手术的长期评估:20年临床及超声心动图随访
Rev Port Cardiol (Engl Ed). 2019 May;38(5):315-321. doi: 10.1016/j.repc.2018.06.014. Epub 2019 Jun 17.
7
Outcomes after Ross procedure in adult patients: A meta-analysis and microsimulation.成人患者Ross手术的术后结果:一项荟萃分析与微观模拟研究
J Card Surg. 2019 May;34(5):285-292. doi: 10.1111/jocs.14020. Epub 2019 Mar 13.
8
The Ross Procedure: A Systematic Review, Meta-Analysis, and Microsimulation.罗斯手术:一项系统评价、荟萃分析和微观模拟研究
Circ Cardiovasc Qual Outcomes. 2018 Dec;11(12):e004748. doi: 10.1161/CIRCOUTCOMES.118.004748.
9
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Eur J Cardiothorac Surg. 2019 May 1;55(5):885-892. doi: 10.1093/ejcts/ezy377.
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Eur J Cardiothorac Surg. 2019 May 1;55(5):876-884. doi: 10.1093/ejcts/ezy372.