Kurysheva N I, Sharova G A
Medical and Biological University of Innovations and Continuing Education of the State Research Center - Burnasyan Federal Biophysical Center, Moscow, Russia.
Ophthalmological Center of the State Research Center - Burnasyan Federal Biophysical Center, Moscow, Russia.
Vestn Oftalmol. 2022;138(4):108-116. doi: 10.17116/oftalma2022138041108.
To review the literature devoted to the search of predictors of primary angle closure (PAC) progression as an important link in the pathogenesis of primary angle-closure glaucoma. This part presents a cluster analysis, describes the mechanisms of PAC development, and considers the studies aimed at discovering the risk factors for the progression of primary angle closure suspect into true angle closure. The results of the analyzed literature are ambiguous, indicating the need for further research that would involve strict inclusion criteria, and a standard approach to defining the primary angle closure disease and expanding the diagnostic parameters, in which a key role belongs to anterior segment optical coherence tomography (AS-OCT).
回顾致力于寻找原发性房角关闭(PAC)进展预测因素的文献,这是原发性闭角型青光眼发病机制中的一个重要环节。本部分进行了聚类分析,描述了PAC的发展机制,并探讨了旨在发现原发性房角关闭可疑患者进展为真正房角关闭的危险因素的研究。分析文献的结果并不明确,这表明需要进一步开展研究,采用严格的纳入标准,运用定义原发性房角关闭疾病的标准方法并扩大诊断参数,其中前段光学相干断层扫描(AS-OCT)起着关键作用。