从大流行中理解迷走神经在健康中的关键作用。
Understanding the Pivotal Role of the Vagus Nerve in Health from Pandemics.
作者信息
Rangon Claire-Marie, Niezgoda Adam
机构信息
Child Neurologist and Pain Specialist, INWE'CARE Medical Center, 92210 Saint-Cloud, France.
Chair and Department of Neurology, University of Medical Sciences, 60-355 Poznań, Poland.
出版信息
Bioengineering (Basel). 2022 Jul 29;9(8):352. doi: 10.3390/bioengineering9080352.
Abstract
The COVID-19 pandemic seems endless with the regular emergence of new variants. Is the SARS-CoV-2 virus particularly evasive to the immune system, or is it merely disrupting communication between the body and the brain, thus pre-empting homeostasis? Retrospective analysis of the COVID-19 and AIDS pandemics, as well as prion disease, emphasizes the pivotal but little-known role of the 10th cranial nerve in health. Considering neuroimmunometabolism from the point of view of the vagus nerve, non-invasive bioengineering solutions aiming at monitoring and stimulating the vagal tone are subsequently discussed as the next optimal and global preventive treatments, far beyond pandemics.
摘要
随着新冠病毒新变种的不断出现，新冠疫情似乎没完没了。是严重急性呼吸综合征冠状病毒2（SARS-CoV-2）特别难以被免疫系统识别，还是它仅仅干扰了身体与大脑之间的通讯，从而破坏了体内平衡？对新冠疫情、艾滋病疫情以及朊病毒疾病的回顾性分析，凸显了第十对脑神经在健康方面关键却鲜为人知的作用。从迷走神经的角度考虑神经免疫代谢，随后将讨论旨在监测和刺激迷走神经张力的非侵入性生物工程解决方案，这些方案作为下一个最佳的全面预防性治疗手段，其作用远远不止于应对疫情。
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