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Genetics of denatonium-responsive bitter receptors in aspirin-exacerbated respiratory disease.

作者信息

Douglas Jennifer E, Lin Cailu, Mansfield Corrine J, Bell Katherine, Salmon Mandy K, Kohanski Michael A, Adappa Nithin D, Palmer James N, Bosso John V, Reed Danielle R, Cohen Noam A

机构信息

Department of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA.

出版信息

Int Forum Allergy Rhinol. 2023 Mar;13(3):269-272. doi: 10.1002/alr.23077. Epub 2022 Sep 12.

Abstract
摘要

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本文引用的文献

1
Denatonium benzoate bitter taste perception in chronic rhinosinusitis subgroups.
Int Forum Allergy Rhinol. 2021 Jun;11(6):967-975. doi: 10.1002/alr.22687. Epub 2020 Sep 3.
2
Aspirin-Exacerbated Respiratory Disease.
N Engl J Med. 2018 Sep 13;379(11):1060-1070. doi: 10.1056/NEJMra1712125.
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Taste Exam: A Brief and Validated Test.
J Vis Exp. 2018 Aug 17(138):56705. doi: 10.3791/56705.
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Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps.
J Allergy Clin Immunol. 2018 Aug;142(2):460-469.e7. doi: 10.1016/j.jaci.2018.03.019. Epub 2018 May 17.
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Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity.
Am J Rhinol Allergy. 2017 Mar 1;31(2):85-92. doi: 10.2500/ajra.2017.31.4424.
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Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.
Science. 2016 Mar 18;351(6279):1329-33. doi: 10.1126/science.aaf1648. Epub 2016 Feb 4.
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Bitter and sweet taste receptors regulate human upper respiratory innate immunity.
J Clin Invest. 2014 Mar;124(3):1393-405. doi: 10.1172/JCI72094. Epub 2014 Feb 17.
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Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa.
Int Forum Allergy Rhinol. 2013 Jun;3(6):450-7. doi: 10.1002/alr.21149. Epub 2013 Feb 12.
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Expression of taste receptors in solitary chemosensory cells of rodent airways.
BMC Pulm Med. 2011 Jan 13;11:3. doi: 10.1186/1471-2466-11-3.

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