心脏康复对老年慢性心力衰竭患者的影响：荟萃分析和系统评价。
Effects of cardiac rehabilitation on elderly patients with Chronic heart failure: A meta-analysis and systematic review.
机构信息
Department of Cardiovascular Medicine, The Fifth People's Hospital of Jinan, Jinan, Shandong, China.
Department of Emergency, Yidu Central Hospital, Weifang, Shandong, China.
出版信息
PLoS One. 2022 Aug 25;17(8):e0273251. doi: 10.1371/journal.pone.0273251. eCollection 2022.
AIMS
The purpose of this study was to investigate the effects of cardiac rehabilitation (CR) on elderly patients with Chronic heart failure (CHF) by literature search and meta-analysis.
METHODS
We conducted an electronic search on PubMed, Cochrane Library, Embase, CNKI, Wanfang, and VIP database platforms. The search period was from the establishment of the database to November 2021 for randomized controlled studies (RCTs) related to the effects of CR on elderly patients with CHF. The RevMan 5.4 was used for meta-analysis.
RESULTS
This study included 16 articles involving a total of 1782 patients, including 892 in the CR group and 890 in the control group. Meta-analysis showed that compared with conventional interventions, CR increased left ventricular ejection fraction in elderly patients with CHF [mean difference (MD):5.73,95% confidence interval (CI):2.05 to 9.40,Z = 3.05,P = 0.002], and decreased left ventricular end-diastolic diameter in elderly patients with CHF (MD:-4.82,95%CI:-7.49 to 15,Z = 3.54,P = 0.0004), increased the 6-minute walk test distance (MD:62.66,95% CI:44.40 to 80.92,Z = 6.72,P<0.00001), decreased the rehospitalization rate (OR:0.32,95%) CI: 0.21 0.49, Z = 5.33, P < 0.000001).
CONCLUSIONS
CR can improve cardiac function, prognosis and reduce rehospitalization rate of elderly patients with CHF.
目的
本研究旨在通过文献检索和荟萃分析探讨心脏康复（CR）对老年慢性心力衰竭（CHF）患者的影响。
方法
我们在 PubMed、Cochrane Library、Embase、CNKI、万方和 VIP 数据库平台上进行了电子检索。检索时间为从数据库建立到 2021 年 11 月，以获取与 CR 对老年 CHF 患者影响相关的随机对照研究（RCT）。使用 RevMan 5.4 进行荟萃分析。
结果
本研究共纳入 16 篇文章，涉及 1782 例患者，其中 CR 组 892 例，对照组 890 例。荟萃分析结果显示，与常规干预相比，CR 可增加老年 CHF 患者的左心室射血分数[均数差（MD）：5.73，95%置信区间（CI）：2.05 至 9.40，Z = 3.05，P = 0.002]，降低老年 CHF 患者的左心室舒张末期内径（MD：-4.82，95%CI：-7.49 至 15，Z = 3.54，P = 0.0004），增加 6 分钟步行试验距离（MD：62.66，95%CI：44.40 至 80.92，Z = 6.72，P<0.00001），降低再住院率（OR：0.32，95%CI：0.21 至 0.49，Z = 5.33，P < 0.000001）。
结论
CR 可改善老年 CHF 患者的心脏功能、预后，并降低再住院率。
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