Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria; Mountain Top University, Ogun State, Nigeria.
Ahmadu Bello University, Zaria, Nigeria.
Res Vet Sci. 2022 Dec 20;152:219-227. doi: 10.1016/j.rvsc.2022.07.028. Epub 2022 Aug 4.
The high rate of antibiotic resistance constitutes a global threat to the continuous use of these drugs, because of increasing treatment failures. The aim of this study was to survey antibiotic prescription practices of veterinarians and the possible contribution to antimicrobial resistance (AMR) and antimicrobial stewardship (AMS) in Nigeria during the COVID era. This was a cross-sectional study that used a 33-question survey questionnaire administered to registered veterinarians in Nigeria. The study was both online survey and hard copy administered during the annual meeting of the veterinarians from July to October 2021. Descriptive statistics, bivariate analysis using Chi-square test were also done to analyze the results, while a two-tailed P-value of <0.05 at 95% confidence level was considered statistically significant. IBM SPSS Version 26 was used to analyze the data. A total of 172 respondents completed the online and hard copy questionnaire. Majority of the respondents engaged majorly in mixed veterinary practice (72.1%). A total of 53.5% were aware of the country's policy concerning antibiotic prescription, while majority (64.5%) do not do culture and sensitivity before antibiotic prescription. Majority (34.3%) felt that the risk of potential adverse drug reaction could affect their decision when choosing to prescribe an antibiotic to the owner. Majority (51.2%) felt that some antibiotics were over prescribed, while 26.7% opined that all antibiotics were appropriately prescribed. To improve antibiotic use and practice amongst veterinarians in Nigeria, dependence on laboratory services for antibiotic prescription, enforcement of national guidelines and monitoring of antibiotic prescription amongst the veterinarians is essential to curb over-prescription and strengthen antimicrobial stewardship.
抗生素耐药率高，导致治疗失败不断增加，对这些药物的持续使用构成了全球性威胁。本研究旨在调查尼日利亚兽医的抗生素处方实践，以及这些实践对抗生素耐药性（AMR）和抗菌药物管理（AMS）的可能贡献。这是一项横断面研究，使用了一份 33 个问题的调查问卷，对尼日利亚注册兽医进行了调查。该研究是在 2021 年 7 月至 10 月期间兽医年度会议期间通过在线调查和纸质问卷进行的。还进行了描述性统计和使用卡方检验的二变量分析来分析结果，同时以 95%置信水平的双侧 P 值<0.05 为统计学显著。使用 IBM SPSS 版本 26 分析数据。共有 172 名受访者完成了在线和纸质问卷。大多数受访者主要从事混合兽医实践（72.1%）。共有 53.5%的人了解该国关于抗生素处方的政策，而大多数（64.5%）在开抗生素处方前不做培养和药敏试验。大多数（34.3%）人认为潜在药物不良反应的风险可能会影响他们选择给主人开抗生素的决定。大多数（51.2%）人认为某些抗生素被过度开方，而 26.7%的人认为所有抗生素都得到了适当的开方。为了改善尼日利亚兽医对抗生素的使用和实践，依赖实验室服务开抗生素处方、执行国家指南和监测兽医的抗生素处方对于遏制过度开方和加强抗菌药物管理至关重要。
