Bangladesh Livestock Research Institute (BLRI), Antimicrobial Resistance Action Center (ARAC), Savar, Dhaka, Bangladesh.
Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh.
PLoS One. 2024 Aug 13;19(8):e0308324. doi: 10.1371/journal.pone.0308324. eCollection 2024.
The emergence of antimicrobial resistance is a growing human and animal health concern around the world. When a number of studies have emphasized the Knowledge, Attitude and Practice (KAP) regarding antibiotic use and resistance in humans, little attention has been paid to the veterinary sector. The aim of this study was to understand the KAP towards antibiotic use and resistance among veterinarians in Bangladesh.
A cross-sectional online based questionnaire survey was conducted from August to September 2020 among the registered veterinary practitioners. A self-administered Google form questionnaire consisting of 45 questions on knowledge, attitude and practice regarding antibiotic use and resistance was used. For statistical significance test we used Chi-square or Fisher's Exact test and logistic regression for factor analysis.
A total of 208 registered veterinarians participated in this study. The study involved a majority of male participants, constituting 85.1%, while 54.8% of the participants held a Masters degree. Around 52% of the veterinarians were poultry practitioners. All respondents were familiar with antimicrobials. The participants (91.4%) knew that antibiotics cannot cure viral infections, while 97.6% believed that frequent antibiotic prescriptions rendered them less effective. Participants claimed that only they were eligible to prescribe drugs for the treatment of animals, and around 80% disagreed with adding antibiotics with feed/water as a growth promoter in livestock. Of the total participants, 87% believed that a local antimicrobial guideline would be more effective than an international one. A multivariable analysis revealed that male veterinarians have 2.37 times higher knowledge regarding antimicrobial use (AMU) and antimicrobial resistance (AMR) (OR = 2.37, CI = 1.01-5.59, p = 0.05). Veterinarians engaged in government services demonstrated a 2.59 times more favorable attitude towards AMU and AMR (OR = 2.59, CI = 0.99-6.73, p = 0.05). Additionally, respondents aged 31-35 were 0.45 times more likely to exhibit good practices (OR = 0.45, CI = 0.2-1.00, p = 0.05). However, gaps in practices were highlighted in our study, suggesting training deficiencies.
The present study, for the first time conducted in Bangladesh, dictates that future interventions like academic courses, workshops, and seminars on antibiotic usage and resistance are needed to facilitate the knowledge, behavior and practice of veterinarians with regard to the rational use of antibiotics.
抗菌药物耐药性的出现是全球人类和动物健康日益关注的问题。虽然有许多研究强调了人类对抗生素使用和耐药性的知识、态度和实践（KAP），但兽医领域却很少受到关注。本研究旨在了解孟加拉国兽医对抗生素使用和耐药性的知识、态度和实践。
2020 年 8 月至 9 月期间，采用在线横断面问卷调查的方式，对注册兽医从业者进行了调查。使用包含 45 个关于抗生素使用和耐药性的知识、态度和实践问题的自我管理谷歌表格问卷。为了进行统计显著性检验，我们使用了卡方检验或 Fisher 精确检验和逻辑回归进行因素分析。
共有 208 名注册兽医参与了这项研究。研究对象主要为男性，占 85.1%，而参与者中有 54.8%拥有硕士学位。大约 52%的兽医是家禽从业者。所有受访者都熟悉抗菌药物。91.4%的参与者知道抗生素不能治疗病毒感染，而 97.6%的参与者认为频繁开具抗生素处方会降低其疗效。参与者声称只有他们有资格为动物治疗开具药物，约 80%的人不同意在牲畜饲料/水中添加抗生素作为生长促进剂。在所有参与者中，87%的人认为当地的抗菌药物指南比国际指南更有效。多变量分析显示，男性兽医对抗生素使用（AMU）和抗菌药物耐药性（AMR）的知识要高出 2.37 倍（OR=2.37，CI=1.01-5.59，p=0.05）。在政府部门工作的兽医对 AMU 和 AMR 的态度更为有利，高出 2.59 倍（OR=2.59，CI=0.99-6.73，p=0.05）。此外，年龄在 31-35 岁的受访者表现出良好实践的可能性要低 0.45 倍（OR=0.45，CI=0.2-1.00，p=0.05）。然而，我们的研究也凸显了实践中的差距，表明存在培训不足的问题。
本研究首次在孟加拉国进行，表明需要开展学术课程、研讨会和研讨会等未来干预措施，以提高兽医对抗生素使用和耐药性的知识、行为和实践，促进合理使用抗生素。
