Zhou Yujia, Chang Peter, Abdelmalik Bishoy, Mayer Zachary, Shah Ankit, Steigleman Walter A
University of Florida Shands Hospital (Y.Z., B.A., Z.M., A.S., W.A.S, .), Gainesville, Florida, USA.
University of Florida Department of Biostatistics (P.C.), Gainesville, Florida, USA.
Am J Ophthalmol. 2022 Dec;244:152-165. doi: 10.1016/j.ajo.2022.08.015. Epub 2022 Aug 23.
To analyze vision outcomes after open globe injury and propose modifications to the ocular trauma score to offer more specific vision prognoses.
Validity and reliability analysis.
Patients presenting to the University of Florida with a new open globe injury from October 2015 to January 2021 with subsequent follow-up were included in the study. Demographics, ophthalmic history, trauma details, timeline, imaging, operative findings, and ocular examinations were collected from the medical record. Z tests, χ test, Fisher exact test, receiver operating characteristic curve, and ordinal correlation were used. A weighted logistic model was optimized to predict vision outcomes. Measured outcomes included the best-corrected visual acuity, Ocular Trauma Score category, and performance of vision prognosis scores.
A total of 162 eyes were identified from chart review. Eighty percent of the Ocular Trauma Score categories were accurate. Only the absence of orbital fractures was associated with a significant weight in the logistic model, which produced more accurate prognoses for 59 patients, and less accurate prognoses for 30 patients compared to the Ocular Trauma Score. Kendall Tau-B was 0.639 for the logistic model and 0.582 for the Ocular Trauma Score.
The Ocular Trauma Score accurately estimates vision prognosis after open globe injury. We propose inclusion of orbital fracture status in our Modified Florida Ocular Trauma Score. This addended score is more correlated with final vision outcome and provides more specific prognoses for severe open globe injuries. Prospective, multicenter validation is needed to refine and confirm the use of this new scoring system.
分析开放性眼球损伤后的视力预后,并对眼外伤评分进行修改,以提供更具体的视力预后评估。
效度和信度分析。
纳入2015年10月至2021年1月在佛罗里达大学因新发开放性眼球损伤并随后接受随访的患者。从病历中收集人口统计学资料、眼科病史、外伤细节、时间线、影像学检查、手术发现和眼部检查结果。使用Z检验、χ检验、Fisher精确检验、受试者工作特征曲线和等级相关性分析。优化加权逻辑模型以预测视力预后。测量的结果包括最佳矫正视力、眼外伤评分类别和视力预后评分的表现。
通过病历回顾共识别出162只眼。眼外伤评分类别的准确率为80%。在逻辑模型中,仅眼眶骨折的缺失具有显著权重,与眼外伤评分相比,该模型对59例患者的预后预测更准确,对30例患者的预后预测不准确。逻辑模型的肯德尔tau-B系数为0.639,眼外伤评分为0.582。
眼外伤评分能准确估计开放性眼球损伤后的视力预后。我们建议在改良的佛罗里达眼外伤评分中纳入眼眶骨折状态。这个附加评分与最终视力结果的相关性更强,为严重开放性眼球损伤提供了更具体的预后评估。需要进行前瞻性、多中心验证以完善和确认这个新评分系统的应用。