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亚太经合组织经济体综合抗菌药物耐药性监测与控制策略的进展:对一个多年能力建设项目的评估

Advances in Integrated Antimicrobial Resistance Surveillance and Control Strategies in Asia-Pacific Economic Cooperation Economies: Assessment of a Multiyear Building Capacity Project.

作者信息

Cornejo Javiera, Asenjo Gabriela, Zavala Sebastian, Venegas Lucas, Galarce Nicolás, Hormazábal Juan Carlos, Vergara-E Constanza, Lapierre Lisette

机构信息

Departamento de Medicina Preventiva Animal, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile.

Grupo Colaborativo Una Salud-Chile, Santiago 8820808, Chile.

出版信息

Antibiotics (Basel). 2022 Jul 29;11(8):1022. doi: 10.3390/antibiotics11081022.

DOI:10.3390/antibiotics11081022
PMID:36009891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9405055/
Abstract

Antimicrobial resistance (AMR) is a growing global health concern for both animal and public health, and collaborative strategies are needed to combat the threat. The level of awareness and funding for policies focused on reducing AMR varies between countries. The aim of this study was to compare the integrated surveillance systems for AMR in high and low-middle economies of the Asia-Pacific Economic Cooperation and determine whether there was any improvement from 2015 to 2018. We conducted a survey with a group of 21 countries at different development levels. Associations between the economic development level and the questions of AMR awareness and funding were established using Fisher's exact test. Improvements were identified where countries established public policies for integrated surveillance of AMR. High economies showed greater advancement in several topics related to AMR than low-middle economies. The survey revealed that there is a better understanding surrounding the implications of the emergence of AMR in human medicine than in veterinary medicine, agriculture, and food production. Our results show that countries enhanced overall AMR surveillance over the 4-year-period; however, more research is needed concerning these advances, especially in low-middle economies and the food production sector.

摘要

抗菌药物耐药性(AMR)对动物健康和公共卫生而言都是一个日益严重的全球健康问题,因此需要采取合作策略来应对这一威胁。各国针对减少AMR的政策的认知水平和资金投入各不相同。本研究的目的是比较亚太经合组织高收入和中低收入经济体中AMR的综合监测系统,并确定2015年至2018年期间是否有任何改进。我们对21个不同发展水平的国家进行了一项调查。使用Fisher精确检验确定经济发展水平与AMR认知和资金投入问题之间的关联。在各国制定AMR综合监测公共政策的方面发现了改进之处。高收入经济体在与AMR相关的几个主题上比中低收入经济体取得了更大进展。调查显示,相比兽医学、农业和食品生产领域,人们对AMR在人类医学中出现的影响有更好的理解。我们的结果表明,各国在这4年期间加强了整体AMR监测;然而,需要对这些进展进行更多研究,特别是在中低收入经济体和食品生产部门。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cf/9405055/2903eecb8e43/antibiotics-11-01022-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cf/9405055/2903eecb8e43/antibiotics-11-01022-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78cf/9405055/2903eecb8e43/antibiotics-11-01022-g001.jpg

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Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.2019 年全球细菌对抗菌药物耐药性的负担:系统分析。
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An insight into the implementation of the global action plan on antimicrobial resistance in the WHO African region: A roadmap for action.深入了解世界卫生组织非洲区域抗菌药物耐药性全球行动计划的实施情况:行动路线图
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An analysis of national action plans on antimicrobial resistance in Southeast Asia using a governance framework approach.
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Antibiotic resistance surveillance systems: A review.抗生素耐药性监测系统:综述。
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Antibiotic drug-resistance as a complex system driven by socio-economic growth and antibiotic misuse.抗生素耐药性作为一个由社会经济增长和抗生素滥用驱动的复杂系统。
Sci Rep. 2019 Jul 5;9(1):9788. doi: 10.1038/s41598-019-46078-y.
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Clinical and economic impact of antibiotic resistance in developing countries: A systematic review and meta-analysis.发展中国家抗生素耐药性的临床和经济影响:一项系统评价与荟萃分析
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Antibiotic stewardship in low- and middle-income countries: the same but different?中低收入国家的抗生素管理:相同但又不同?
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