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小儿开放性长骨骨折及后续深部感染风险:早期医院护理的重要性。

Pediatric Open Long-Bone Fracture and Subsequent Deep Infection Risk: The Importance of Early Hospital Care.

作者信息

Kuhn Andrew W, Troyer Stockton C, Martus Jeffrey E

机构信息

Department of Orthopedic Surgery, Washington University in St. Louis, St. Louis, MO 63108, USA.

Washington University School of Medicine in St. Louis, St. Louis, MO 63108, USA.

出版信息

Children (Basel). 2022 Aug 17;9(8):1243. doi: 10.3390/children9081243.

Abstract

The purpose of the current study was to identify risk factors for deep infection after an open long-bone fracture in pediatric patients. Systematic billing queries were utilized to identify pediatric patients who presented to a level I trauma center from 1998 to 2019 with open long-bone fractures. There were 303 open long-bone fractures, and 24 (7.9%) of these became infected. Fractures of the tibia/fibula ( 0.022), higher revised Gustilo-Anderson type ( 0.017), and a longer duration of time between the injury and hospital presentation ( 0.008) were all associated with the presence of deep infection. Those who went on to have a deep infection also required more operative debridements ( 0.022) and a total number of operative procedures ( 0.026). The only factor that remained significant in multivariable regression was the duration between the injury and hospital presentation (OR 1.01 [95%CI 1.003-1.017]; 0.009), where the odds of deep infection increased by 1% for every minute of delayed presentation.

摘要

本研究的目的是确定小儿患者开放性长骨骨折后深部感染的危险因素。利用系统计费查询来确定1998年至2019年期间在一级创伤中心就诊的开放性长骨骨折小儿患者。共有303例开放性长骨骨折,其中24例(7.9%)发生感染。胫腓骨骨折(0.022)、较高的改良Gustilo-Anderson分型(0.017)以及受伤至入院之间的时间较长(0.008)均与深部感染的发生相关。发生深部感染的患者还需要更多的手术清创(0.022)和手术总次数(0.026)。多变量回归中唯一仍具有显著性的因素是受伤至入院之间的时间(比值比1.01[95%置信区间1.003-1.017];P=0.009),即延迟就诊每增加一分钟,深部感染的几率增加1%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/749a/9406608/f1f5950c1804/children-09-01243-g001.jpg

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