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酷似分化型甲状腺癌转移的强放射性碘阳性胰腺腺癌

Strongly Radioiodine-Positive Pancreatic Adenocarcinoma Mimicking Metastasis of Differentiated Thyroid Cancer.

作者信息

Rosar Florian, Burgard Caroline, Linxweiler Maximilian, Stahl Phillip R, Khreish Fadi, Ezziddin Samer

机构信息

Department of Nuclear Medicine, Saarland University, 66421 Homburg, Germany.

Department of Otorhinolaryngology, Head and Neck Surgery, Saarland University, 66421 Homburg, Germany.

出版信息

Diagnostics (Basel). 2022 Aug 11;12(8):1934. doi: 10.3390/diagnostics12081934.

DOI:10.3390/diagnostics12081934
PMID:36010284
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9406392/
Abstract

We present an interesting image of a strikingly intense radioiodine accumulation of a histologically proven pancreatic adenocarcinoma mimicking metastasis of differentiated thyroid cancer in a 63-year-old woman with recurrence of papillary thyroid carcinoma undergoing radioiodine therapy. This interesting image should draw attention to considering pancreatic adenocarcinoma in radioiodine-positive pancreatic lesions.

摘要

我们展示了一张有趣的图像,该图像显示一名63岁患有乳头状甲状腺癌复发且正在接受放射性碘治疗的女性,其组织学确诊的胰腺腺癌出现了极为强烈的放射性碘摄取,酷似分化型甲状腺癌转移。这一有趣的图像应引起关注,在放射性碘摄取阳性的胰腺病变中需考虑胰腺腺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f7d/9406392/e40a188c39d8/diagnostics-12-01934-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f7d/9406392/c418d3c2bb7e/diagnostics-12-01934-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f7d/9406392/e40a188c39d8/diagnostics-12-01934-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f7d/9406392/c418d3c2bb7e/diagnostics-12-01934-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f7d/9406392/e40a188c39d8/diagnostics-12-01934-g002.jpg

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本文引用的文献

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I-131 false-positive uptake in a thymic cyst with expression of the sodium-iodide symporter: A case report.碘-131 摄取在表达钠碘同向转运体的胸腺囊肿中的假阳性摄取:病例报告。
Medicine (Baltimore). 2022 Jul 1;101(26):e29282. doi: 10.1097/MD.0000000000029282.
2
Pancreatic metastasis from papillary thyroid carcinoma: Case report and literature review.甲状腺乳头状癌胰腺转移:病例报告及文献复习。
Hell J Nucl Med. 2021 May-Aug;24(2):140-148. doi: 10.1967/s002449912354. Epub 2021 Aug 6.
3
Initial Diagnosis and Staging of Pancreatic Cancer Including Main Differentials.
胰腺癌的初始诊断与分期,包括主要鉴别诊断。
Semin Ultrasound CT MR. 2019 Dec;40(6):436-468. doi: 10.1053/j.sult.2019.08.001. Epub 2019 Aug 30.
4
Unexpected False-positive I-131 Uptake in Patients with Differentiated Thyroid Carcinoma.分化型甲状腺癌患者中意外出现的 I-131 摄取假阳性
Mol Imaging Radionucl Ther. 2018 Oct 9;27(3):99-106. doi: 10.4274/mirt.37450.
5
PANCREAS METASTASES FROM PAPILLARY THYROID CARCINOMA: A REVIEW OF THE LITERATURE.甲状腺乳头状癌胰腺转移:文献综述
Endocr Pract. 2017 Dec;23(12):1425-1429. doi: 10.4158/EP-2017-0001. Epub 2017 Nov 16.
6
Differentiated Thyroid Cancer-Treatment: State of the Art.分化型甲状腺癌的治疗:最新进展
Int J Mol Sci. 2017 Jun 17;18(6):1292. doi: 10.3390/ijms18061292.
7
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.2015年美国甲状腺协会成人甲状腺结节和分化型甲状腺癌管理指南:美国甲状腺协会甲状腺结节和分化型甲状腺癌指南工作组
Thyroid. 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020.
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The Na+/I- symporter (NIS): mechanism and medical impact.钠/碘同向转运体(NIS):机制与医学影响。
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