Pellegrini Matteo, Pulicari Federica, Zampetti Paolo, Scribante Andrea, Spadari Francesco
Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Maxillo-Facial and Odontostomatology Unit, Department of Biomedical Surgical and Dental Sciences, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy.
Healthcare (Basel). 2022 Aug 14;10(8):1537. doi: 10.3390/healthcare10081537.
Biopsy is a surgical procedure performed to collect a portion of tissue or organ for diagnostic studies. The aim of the present manuscript is to describe state-of-the-art major and minor salivary gland biopsy techniques and assess the indications and complications of other salivary gland biopsy techniques. A search was performed using the following MeSH terms: biopsy, fine-needle biopsies, image-guided biopsies, frozen sections, and salivary glands disease. A current overview of major and minor salivary glands biopsy techniques was provided. In the oncological field, a comparison was made between the most widely used biopsy method, ultrasound-guided fine-needle aspiration biopsy (US-FNAB), and an alternative method, ultrasound-guided core needle biopsy (US-guided CNB), highlighting the advantages and disadvantages of each. Finally, intra-operative frozen sections (IOFSs) were presented as an additional intraoperative diagnostic method. Minor salivary gland biopsy (MSGB) is the simplest diagnostic method used by clinicians in the diagnosis of inflammatory and autoimmune diseases. In neoplastic lesions, US-FNAB represents the most performed method; however, due to its low diagnostic accuracy for non-neoplastic specimens, US-guided CNB has been introduced as an alternative method.
活检是一种外科手术，用于采集一部分组织或器官进行诊断研究。本手稿的目的是描述当前最先进的大、小唾液腺活检技术，并评估其他唾液腺活检技术的适应症和并发症。使用以下医学主题词进行了检索：活检、细针活检、影像引导活检、冰冻切片和唾液腺疾病。提供了大、小唾液腺活检技术的当前概述。在肿瘤学领域，对最广泛使用的活检方法——超声引导细针穿刺活检（US-FNAB）和另一种方法——超声引导粗针活检（US-guided CNB）进行了比较，突出了每种方法的优缺点。最后，术中冰冻切片（IOFSs）作为一种额外的术中诊断方法被提出。小唾液腺活检（MSGB）是临床医生在诊断炎症性和自身免疫性疾病时使用的最简单的诊断方法。在肿瘤性病变中，US-FNAB是最常用的方法；然而，由于其对非肿瘤标本的诊断准确性较低，US-guided CNB已作为一种替代方法被引入。
