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疗养院居民的谵妄:一项叙述性综述。

Delirium in Nursing Home Residents: A Narrative Review.

作者信息

Komici Klara, Guerra Germano, Addona Franco, Fantini Carlo

机构信息

Department of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.

Department of Mental Health, ASREM, Antonio Cardarelli Hospital, 86100 Campobasso, Italy.

出版信息

Healthcare (Basel). 2022 Aug 15;10(8):1544. doi: 10.3390/healthcare10081544.

DOI:10.3390/healthcare10081544
PMID:36011202
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9407867/
Abstract

Delirium is an important component of the geriatric syndromes and has been recognized to negatively influence the prognosis of older people in hospital and in a post-acute setting. About 2-5% of older people world-wide live in nursing homes and are characterized by functional impairment, cognitive decline, dementia, comorbidities, and polypharmacotherapy, all factors which influence the development of delirium. However, in this setting, delirium remains often understudied. Therefore, in this narrative review, we aimed to describe the latest evidence regarding delirium screening tools, epidemiology characteristics, outcomes, risk factors, and preventions strategies in nursing homes.

摘要

谵妄是老年综合征的一个重要组成部分,并且已被认识到会对住院及急性后期环境中的老年人预后产生负面影响。全球约2%-5%的老年人居住在养老院,其特点是功能障碍、认知衰退、痴呆、合并症和多重药物治疗,所有这些因素都会影响谵妄的发生。然而,在这种环境下,谵妄往往仍未得到充分研究。因此,在这篇叙述性综述中,我们旨在描述有关养老院中谵妄筛查工具、流行病学特征、结局、危险因素及预防策略的最新证据。

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1
Delirium in Nursing Home Residents: A Narrative Review.疗养院居民的谵妄:一项叙述性综述。
Healthcare (Basel). 2022 Aug 15;10(8):1544. doi: 10.3390/healthcare10081544.
2
Delirium during acute illness in nursing home residents.养老院居民急性疾病期间的意识混乱。
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Clinical characteristics associated with the onset of delirium among long-term nursing home residents.与长期养老院居民谵妄发作相关的临床特征。
BMC Geriatr. 2018 Feb 2;18(1):39. doi: 10.1186/s12877-018-0733-3.
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A prospective observational study to investigate utility of the Delirium Observational Screening Scale (DOSS) to detect delirium in care home residents.一项前瞻性观察研究,旨在调查 Delirium Observational Screening Scale (DOSS) 在检测养老院居民谵妄中的效用。
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Preliminary Data: An Adapted Hospital Elder Life Program to Prevent Delirium and Reduce Complications of Acute Illness in Long-Term Care Delivered by Certified Nursing Assistants.初步数据:一项经过改编的医院老年生活计划,由认证护理助理在长期护理中预防谵妄并减少急性疾病的并发症。
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Interactions between drugs and geriatric syndromes in nursing home and home care: results from Shelter and IBenC projects.养老机构和家庭护理中药物与老年综合征的相互作用:Shelter 和 IBenC 项目的结果。
Aging Clin Exp Res. 2018 Sep;30(9):1015-1021. doi: 10.1007/s40520-018-0893-1. Epub 2018 Jan 16.
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Study protocol-investigation of the Delirium Observation Screening Scale (DOSS) for the routine detection of delirium in the care home setting: a prospective cohort study.研究方案——谵妄观察筛查量表(DOSS)用于养老院环境中谵妄常规检测的调查:一项前瞻性队列研究。
BMJ Open. 2016 Jun 20;6(6):e009615. doi: 10.1136/bmjopen-2015-009615.
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Interventions for preventing delirium in older people in institutional long-term care.机构长期照护中预防老年人谵妄的干预措施。
Cochrane Database Syst Rev. 2019 Apr 23;4(4):CD009537. doi: 10.1002/14651858.CD009537.pub3.
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Delirium Predisposing and Triggering Factors in Nursing Home Residents: A Cohort Trial-Nested Case-Control Study.养老院居民谵妄的诱发和促发因素:一项队列试验-巢式病例对照研究。
J Alzheimers Dis. 2019;70(4):1113-1122. doi: 10.3233/JAD-190391.
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[Management of elderly patients with delirium or dementia in Swiss nursing homes].[瑞士养老院中谵妄或痴呆老年患者的管理]
Rev Med Suisse. 2007 Nov 7;3(132):2519-20, 2522, 2524 passim.

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Prevalence of delirium in German nursing homes: protocol for a cross-sectional study.德国养老院中谵妄的患病率:一项横断面研究方案
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本文引用的文献

1
Delirium after COVID-19 vaccination in nursing home residents: A case series.养老院居民接种新冠疫苗后出现谵妄:病例系列
J Am Geriatr Soc. 2022 Jun;70(6):1648-1651. doi: 10.1111/jgs.17814. Epub 2022 Apr 27.
2
Detecting delirium in nursing home residents using the Informant Assessment of Geriatric Delirium (I-AGeD): a validation pilot study.使用 Informant Assessment of Geriatric Delirium(I-AGeD)在养老院居民中检测谵妄:一项验证性试点研究。
Eur Geriatr Med. 2022 Aug;13(4):917-931. doi: 10.1007/s41999-022-00612-w. Epub 2022 Feb 10.
3
Delirium During Acute Events in Nursing Home Patients.疗养院患者急性事件期间的谵妄
J Am Med Dir Assoc. 2022 Jan;23(1):146-149. doi: 10.1016/j.jamda.2021.10.006. Epub 2021 Nov 10.
4
The prevalence of delirium in belgian nursing homes: a cross-sectional evaluation.比利时养老院谵妄的患病率:一项横断面评估。
BMC Geriatr. 2021 Nov 6;21(1):634. doi: 10.1186/s12877-021-02517-y.
5
The doll therapy as a first line treatment for behavioral and psychologic symptoms of dementia in nursing homes residents: a randomized, controlled study.玩偶疗法作为养老院居民痴呆行为和心理症状的一线治疗方法:一项随机对照研究。
BMC Geriatr. 2021 Oct 12;21(1):545. doi: 10.1186/s12877-021-02496-0.
6
The association between low skeletal muscle mass and delirium: results from the nationwide multi-centre Italian Delirium Day 2017.低骨骼肌质量与谵妄之间的关联:来自2017年意大利全国多中心谵妄日的结果。
Aging Clin Exp Res. 2022 Feb;34(2):349-357. doi: 10.1007/s40520-021-01950-8. Epub 2021 Aug 20.
7
Delirium: A Marker of Vulnerability in Older People.谵妄:老年人易感性的一个标志
Front Aging Neurosci. 2021 Apr 30;13:626127. doi: 10.3389/fnagi.2021.626127. eCollection 2021.
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Prevalence, incidence and mortality of delirium in patients with COVID-19: a systematic review and meta-analysis.COVID-19 患者谵妄的患病率、发病率和死亡率:系统评价和荟萃分析。
Age Ageing. 2021 Sep 11;50(5):1445-1453. doi: 10.1093/ageing/afab103.
9
Validation of the Delirium Diagnostic Tool-Provisional (DDT-Pro) in a skilled nursing facility and comparison to the 4 'A's test (4AT).在熟练护理机构中验证暂定谵妄诊断工具(DDT-Pro),并与 4 'A' 测试(4AT)进行比较。
Gen Hosp Psychiatry. 2021 May-Jun;70:116-123. doi: 10.1016/j.genhosppsych.2021.03.010. Epub 2021 Mar 29.
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Management and outcomes of a COVID-19 outbreak in a nursing home with predominantly Black residents.一家以黑人为主要居民的养老院中 COVID-19 疫情的管理和结果。
J Am Geriatr Soc. 2021 May;69(5):1155-1165. doi: 10.1111/jgs.17126. Epub 2021 Mar 24.