Department of Epidemiology and Health Statistics, School of Public Health, Chongqing Medical University, Yixue Road, Chongqing 400016, China.
Int J Environ Res Public Health. 2022 Aug 17;19(16):10185. doi: 10.3390/ijerph191610185.
(1) Background: Men who have sex with other men (MSMs) are at high risk of being infected by the human immunodeficiency virus (HIV) in western China. Pre-exposure prophylaxis (PrEP) is an efficient way to prevent HIV transmission. However, adherence is the most vital determinant factor affecting PrEP effectiveness. We conducted a study based on the Health Belief Model to explore factors that predict adherence to PrEP among a cohort of 689 MSMs in western China. (2) Methods: We assessed perceived susceptibility, severity, benefits, barriers, self-efficacy, cues to action, and HIV-preventive behavior through a cross-sectional survey. (3) Results: PrEP self-efficacy was directly associated with PrEP behaviors (β = 0.221, p < 0.001), cues to action were directly associated with PrEP behaviors (β = 0.112, p < 0.001), perceived benefits were directly associated with PrEP behaviors (β = 0.101, p < 0.001), and perceived susceptibility was directly associated with PrEP behaviors (β = 0.117, p = 0.043). (4) Conclusion: Medication self-efficacy, perceived susceptibility, and cue to action structures are predictors of the MSMs’ HIV-preventive behavior in western China. These results will provide theoretical plans for promoting PrEP adherence in MSMs.
(1) 背景：在中国西部，男男性行为者（MSM）感染人类免疫缺陷病毒（HIV）的风险很高。暴露前预防（PrEP）是预防 HIV 传播的有效方法。然而，坚持是影响 PrEP 效果的最关键决定因素。我们基于健康信念模型，对中国西部的 689 名 MSM 队列进行了一项研究，以探讨影响其坚持 PrEP 的因素。
(2) 方法：我们通过横断面调查评估了感知易感性、严重性、益处、障碍、自我效能、提示因素和 HIV 预防行为。
(3) 结果：PrEP 自我效能直接与 PrEP 行为相关（β=0.221，p<0.001），提示因素直接与 PrEP 行为相关（β=0.112，p<0.001），感知益处直接与 PrEP 行为相关（β=0.101，p<0.001），感知易感性直接与 PrEP 行为相关（β=0.117，p=0.043）。
(4) 结论：药物自我效能、感知易感性和提示因素结构是中国西部 MSM 预防 HIV 行为的预测因素。这些结果将为促进 MSM 坚持 PrEP 提供理论计划。
