Miyata Y, Nakano S, Yasuda H
Neurosci Res. 1987 Apr;4(4):268-78. doi: 10.1016/0168-0102(87)90043-5.
In the spinal cord isolated from neonatal rats, stimulation of the ipsilateral lateral column at the thoracic level strongly inhibited monosynaptic segmental reflex in the lumbar cord for about 60 s. The descending inhibition was not associated with any changes in the membrane potential or conductance in lumbar motoneurons when the excitatory postsynaptic potentials in response to stimulation of the dorsal root were depressed. The descending inhibition was diminished with age and could not be detected at 5 months of age. It is suggested that certain inhibitory pathways in the descending spinal tract are rearranged during postnatal development of rats.
在从新生大鼠分离出的脊髓中,刺激胸段同侧外侧柱可强烈抑制腰段脊髓的单突触节段反射约60秒。当对背根刺激的兴奋性突触后电位受到抑制时,下行抑制与腰段运动神经元的膜电位或电导的任何变化均无关。下行抑制随年龄增长而减弱,在5月龄时无法检测到。提示在大鼠出生后的发育过程中,脊髓下行传导束中的某些抑制性通路发生了重排。