• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠脊髓反射中产后短暂表达的持久下行抑制作用

Postnatal transient expression of long-lasting descending inhibitory effect on spinal reflexes in the rat.

作者信息

Miyata Y, Nakano S, Yasuda H

出版信息

Neurosci Res. 1987 Apr;4(4):268-78. doi: 10.1016/0168-0102(87)90043-5.

DOI:10.1016/0168-0102(87)90043-5
PMID:3601245
Abstract

In the spinal cord isolated from neonatal rats, stimulation of the ipsilateral lateral column at the thoracic level strongly inhibited monosynaptic segmental reflex in the lumbar cord for about 60 s. The descending inhibition was not associated with any changes in the membrane potential or conductance in lumbar motoneurons when the excitatory postsynaptic potentials in response to stimulation of the dorsal root were depressed. The descending inhibition was diminished with age and could not be detected at 5 months of age. It is suggested that certain inhibitory pathways in the descending spinal tract are rearranged during postnatal development of rats.

摘要

在从新生大鼠分离出的脊髓中,刺激胸段同侧外侧柱可强烈抑制腰段脊髓的单突触节段反射约60秒。当对背根刺激的兴奋性突触后电位受到抑制时,下行抑制与腰段运动神经元的膜电位或电导的任何变化均无关。下行抑制随年龄增长而减弱,在5月龄时无法检测到。提示在大鼠出生后的发育过程中,脊髓下行传导束中的某些抑制性通路发生了重排。

相似文献

1
Postnatal transient expression of long-lasting descending inhibitory effect on spinal reflexes in the rat.大鼠脊髓反射中产后短暂表达的持久下行抑制作用
Neurosci Res. 1987 Apr;4(4):268-78. doi: 10.1016/0168-0102(87)90043-5.
2
Serotonergic fibers induce a long-lasting inhibition of monosynaptic reflex in the neonatal rat spinal cord.5-羟色胺能纤维对新生大鼠脊髓单突触反射产生持久抑制作用。
Neuroscience. 1992;47(3):521-31. doi: 10.1016/0306-4522(92)90162-u.
3
Muscarinic excitatory and inhibitory mechanisms involved in afferent fibre-evoked depolarization of motoneurones in the neonatal rat spinal cord.新生大鼠脊髓中运动神经元传入纤维诱发去极化所涉及的毒蕈碱兴奋和抑制机制。
Br J Pharmacol. 1993 Sep;110(1):61-70. doi: 10.1111/j.1476-5381.1993.tb13772.x.
4
Is 5-hydroxytryptamine mediating descending inhibition in the neonatal rat spinal cord through different receptor subtypes?5-羟色胺是否通过不同的受体亚型介导新生大鼠脊髓的下行抑制?
Eur J Pharmacol. 1993 Dec 21;250(3):371-7. doi: 10.1016/0014-2999(93)90023-b.
5
Cutaneous nerve-evoked cholinergic inhibition of monosynaptic reflex in the neonatal rat spinal cord: involvement on M2 receptors and tachykininergic primary afferents.新生大鼠脊髓中皮肤神经诱发的单突触反射胆碱能抑制:M2 受体和速激肽能初级传入神经的参与
Neuroscience. 1990;38(1):195-203. doi: 10.1016/0306-4522(90)90385-h.
6
In vitro studies of prolonged synaptic depression in the neonatal rat spinal cord.新生大鼠脊髓中长时间突触抑制的体外研究。
J Physiol. 1992 Feb;447:149-69. doi: 10.1113/jphysiol.1992.sp018996.
7
Antidromic discharges of dorsal root afferents and inhibition of the lumbar monosynaptic reflex in the neonatal rat.新生大鼠背根传入纤维的逆向放电及腰段单突触反射的抑制
Neuroscience. 1999 Apr;90(1):165-76. doi: 10.1016/s0306-4522(98)00435-7.
8
The functional development of descending inhibitory pathways in the dorsolateral funiculus of the newborn rat spinal cord.新生大鼠脊髓背外侧索中下行抑制通路的功能发育
Brain Res. 1986 Jan;389(1-2):261-70. doi: 10.1016/0165-3806(86)90194-x.
9
The role of substance P as a neurotransmitter in the reflexes of slow time courses in the neonatal rat spinal cord.P物质作为神经递质在新生大鼠脊髓慢时程反射中的作用。
Br J Pharmacol. 1985 Mar;84(3):663-73. doi: 10.1111/j.1476-5381.1985.tb16148.x.
10
Inhibitory effects of galanin on the isolated spinal cord of the newborn rat.
Neurosci Lett. 1986 Oct 8;70(2):278-82. doi: 10.1016/0304-3940(86)90477-5.

引用本文的文献

1
Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.5-羟色胺受体激动剂在新生大鼠脊髓中的酮色林敏感的抑制作用。
Br J Pharmacol. 1995 Nov;116(6):2647-54. doi: 10.1111/j.1476-5381.1995.tb17221.x.