De Paulis Stefano, Arlotta Gabriella, Calabrese Maria, Corsi Filippo, Taccheri Temistocle, Antoniucci Maria Enrica, Martinelli Lorenzo, Bevilacqua Francesca, Tinelli Giovanni, Cavaliere Franco
Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy.
Department of Cardiovascular Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
J Pers Med. 2022 Aug 22;12(8):1351. doi: 10.3390/jpm12081351.
Vascular surgery patients have multiple comorbidities and are at high risk for perioperative complications. Aortic repair surgery has greatly evolved in recent years, with an increasing predominance of endovascular techniques (EVAR). The incidence of cardiac complications is significantly reduced with endovascular repair, but high-risk patients require postoperative ST-segment monitoring. Open aortic repair may portend a prohibitive risk of respiratory complications that could be a contraindication for surgery. This risk is greatly reduced in the case of an endovascular approach, and general anesthesia should be avoided whenever possible in the case of endovascular repair. Preoperative renal function and postoperative kidney injury are powerful determinants of short- and long-term outcome, so that preoperative risk stratification and secondary prevention are critical tasks. Intraoperative renal protection with selective renal and distal aortic perfusion is essential during open repair. EVAR has lower rates of postoperative renal failure compared to open repair, with approximately half the risk for acute kidney injury (AKI) and one-third of the risk of hemodialysis requirement. Spinal cord ischemia used to be the most distinctive and feared complication of aortic repair. The risk has significantly decreased since the beginning of aortic surgery, with advances in surgical technique and spinal protection protocols, and is lower with endovascular repair. Endovascular repair avoids extensive aortic dissection and aortic cross-clamping and is generally associated with reduced blood loss and less coagulopathy. The intensive care physician must be aware that aortic repair surgery has an impact on every organ system, and the importance of early recognition of organ failure cannot be overemphasized.
血管外科患者存在多种合并症,围手术期并发症风险较高。近年来,主动脉修复手术有了很大进展,血管内技术(EVAR)的应用越来越普遍。血管内修复可显著降低心脏并发症的发生率,但高危患者术后需要进行ST段监测。开放性主动脉修复可能预示着呼吸并发症风险过高,这可能成为手术的禁忌证。采用血管内入路时,这种风险会大大降低,血管内修复时应尽可能避免全身麻醉。术前肾功能和术后肾损伤是短期和长期预后的重要决定因素,因此术前风险分层和二级预防是关键任务。开放性修复术中,选择性肾动脉和远端主动脉灌注进行术中肾保护至关重要。与开放性修复相比,EVAR术后肾衰竭发生率较低,急性肾损伤(AKI)风险约为其一半,需要进行血液透析的风险约为其三分之一。脊髓缺血曾是主动脉修复最独特且令人担忧的并发症。自主动脉手术开展以来,随着手术技术和脊髓保护方案的进步,该风险已显著降低,血管内修复时风险更低。血管内修复避免了广泛的主动脉夹层分离和主动脉阻断,通常与失血量减少和凝血功能障碍减轻相关。重症监护医生必须意识到,主动脉修复手术会对每个器官系统产生影响,早期识别器官功能衰竭的重要性再怎么强调都不为过。