Zlatanova Tanya, Arabadjiev Jeliazko, Kirova-Nedyalkova Galina, Nikova Diana
Department of Medical Oncology, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria.
Clinic of Radiology, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria.
Front Oncol. 2022 Aug 9;12:907321. doi: 10.3389/fonc.2022.907321. eCollection 2022.
Despite the rare incidence of idiopathic pulmonary fibrosis (IPF), coexisting IPF and lung cancer is common. Both diseases have unfavorable outcomes and are often associated with impaired quality of life. In this study, we present a clinical case of a patient with coexisting IPF and lung adenocarcinoma who was successfully treated with nintedanib plus docetaxel as a second-line treatment, and achieved a substantial improvement in the quality of life. To our knowledge, very few cases in the literature address the concurrent treatment of both diseases, which makes this case a valuable illustration of a successful treatment strategy and a basis for future investigations.
尽管特发性肺纤维化（IPF）发病率较低，但IPF与肺癌并存的情况却很常见。这两种疾病的预后都不理想，且常伴有生活质量受损。在本研究中，我们报告了一例IPF与肺腺癌并存的临床病例，该患者接受了尼达尼布联合多西他赛作为二线治疗，并成功治愈，生活质量得到显著改善。据我们所知，文献中很少有同时治疗这两种疾病的案例，因此该病例是成功治疗策略的宝贵例证，也为未来的研究奠定了基础。
