Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, 030001 Shanxi, China.
Dis Markers. 2022 Aug 16;2022:5069918. doi: 10.1155/2022/5069918. eCollection 2022.
To explore the effects of pamidronate disodium combined with calcium on BMD values and the severity of pain in elderly patients with osteoporosis based on the mobile terminal platform for the Internet of Things.
The data of 120 patients admitted to our hospital from January 2019 to December 2020 were retrospectively analyzed. According to the patients' condition and medication wills, they were divided into the experimental group ( = 68) and the control group ( = 52). All patients were given chronic disease management based on the mobile terminals for the Internet of Things, and they received the treatment of bisphosphonates and calcium, with the supplement of calcium at a daily dose of 1000 mg. The control group was given alendronate sodium once a week, and the experimental group was given pamidronate disodium by intravenous infusion three times a month, with the treatment cycle as 1 year. The patients' bone mineral density (BMD) values and the pain indexes were compared after treatment.
There was no statistical difference in general information between the two groups ( > 0.05). The BMD values of the lumbar vertebrae L, total hip, and femur neck at 6 months and 1 year after treatment in the experimental group were significantly higher than those in the control group ( < 0.001). The pain scores at 6 months and 1 year after treatment in the experimental group were significantly lower than those in the control group ( < 0.001).
The treatment of pamidronate disodium combined with calcium based on the mobile terminal platform for the Internet of Things can reduce the severity of pain in elderly patients with osteoporosis and improve the BMD, which has a generalization value.
基于物联网移动终端平台，探讨帕米膦酸钠二钠联合钙对骨质疏松老年患者骨密度值和疼痛程度的影响。
回顾性分析 2019 年 1 月至 2020 年 12 月我院收治的 120 例患者资料，根据患者病情及用药意愿分为实验组（n=68）和对照组（n=52）。两组患者均基于物联网移动终端进行慢性病管理，给予双膦酸盐和钙治疗，钙补充剂量为 1000 mg/d。对照组给予阿仑膦酸钠每周 1 次，实验组给予帕米膦酸钠二钠静脉滴注，每月 3 次，治疗周期为 1 年。比较两组患者治疗后骨密度值及疼痛指数。
两组患者一般资料比较，差异无统计学意义（>0.05）。治疗后 6 个月、1 年，实验组患者腰椎 L、全髋、股骨颈骨密度值均明显高于对照组（<0.001）。治疗后 6 个月、1 年，实验组患者疼痛评分均明显低于对照组（<0.001）。
基于物联网移动终端平台治疗帕米膦酸钠二钠联合钙能减轻骨质疏松老年患者疼痛程度，提高骨密度，具有推广价值。
