Stura M, Arigliani R, Molinari A C, Tarantino V
Pediatr Med Chir. 1986 Sep-Oct;8(5):703-5.
We examined the auditory function of 29 subjects affected by homozygous beta-thalassemia, managed with an high transfusion scheme and regularly treated with 40-60 mg/kg/day of desferrioxamine. A group of 29 healthy subjects is studied as control. We found conductive hearing defect in 8 thalassemics (6 bilateral) and sensory-neural hearing loss at high frequencies in 4. Thalassemic patients showed more auditory impairment than controls, an higher incidence of tonsillar hypertrophy, adenotonsillitis and submandibular lymph-node enlargement.
我们检查了29名患有纯合子β地中海贫血的受试者的听觉功能,这些受试者采用高输血方案治疗,并定期接受每日40 - 60毫克/千克去铁胺的治疗。选取29名健康受试者作为对照组进行研究。我们发现8名地中海贫血患者存在传导性听力缺陷(6例双侧),4名患者存在高频感音神经性听力损失。地中海贫血患者比对照组表现出更多的听觉损伤,扁桃体肥大、腺扁桃体炎和下颌下淋巴结肿大的发生率更高。