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[儿童癫痫持续状态]

[Status epilepticus in childhood].

作者信息

Vigevano F

出版信息

Pediatr Med Chir. 1986 Nov-Dec;8(6):779-85.

PMID:3601709
Abstract

Status Epilepticus (SE) is defined as an epileptic seizure which is so frequently repeated or so prolonged as to create a fixed and lasting epileptic condition. SE is observed in all age groups, but its frequency increases among younger children. Etiological factors vary with age. During infancy acute encephalopathies (infectious, anoxic-ischaemic, metabolic, etc.) are prevalent, while later non progressive encephalopathies are more frequent. Cryptogenic cases are present in all age groups, but "febrile" cases are observed before two years of age. Generalized forms are rare. The most frequent SE is Unilateral non alternating, which is observed exclusively among children. The semeiological diagnosis of SE with the help of EEG monitoring can be useful, since some forms of SE have constant etiological factors and prognosis. Since the condition of SE may cause brain damage or even endanger patient's life, immediate and adequate treatment is necessary. Diazepam and Phenytoin are particularly effective for stopping the seizures. A practical scheme for treatment is presented.

摘要

癫痫持续状态(SE)被定义为一种癫痫发作,其频繁重复或持续时间过长,从而导致一种固定且持久的癫痫状态。各年龄组均可见SE,但在幼儿中其发生率增加。病因因素随年龄而异。婴儿期急性脑病(感染性、缺氧缺血性、代谢性等)较为普遍,而后期非进行性脑病更为常见。各年龄组均有隐源性病例,但“热性”病例多见于两岁之前。全身性发作形式较为罕见。最常见的SE是单侧非交替性,仅在儿童中观察到。借助脑电图监测对SE进行症状学诊断可能有用,因为某些形式的SE具有恒定的病因因素和预后。由于SE状态可能导致脑损伤甚至危及患者生命,因此需要立即进行充分治疗。地西泮和苯妥英钠对终止发作特别有效。本文提出了一个实用的治疗方案。

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