Catrina A. Calub, University of California, Davis.
Songpoom Benyakorn, Srinakharinwirot University, Bangkok, Thailand.
Am J Intellect Dev Disabil. 2022 Sep 1;127(5):369-389. doi: 10.1352/1944-7558-127.5.369.
This pilot study sought to identify potential markers of improvement from pre-post treatment in response to computerized working memory (WM) training for youth (ages 8-18) with autism spectrum disorder (ASD) and comorbid intellectual disability (ID) in a single arm, pre-post design. Participants included 26 children with ASD and 18 with comorbid ASD and fragile X syndrome (ASD+FXS). Analyses were adjusted for age and IQ. The ASD group demonstrated greater improvement on WM training relative to the ASD+FXS group. Participants improved on WM and far transfer outcomes, however, there were no significant group differences in improvement except for repetitive behavior. Higher hyperactivity/impulsivity ratings predicted lower performance on visuospatial WM. Findings suggest cognitive training may be beneficial for youth with ASD and ID, warranting further exploration.
本初步研究旨在通过单臂前后设计，针对伴有智力障碍（ID）的自闭症谱系障碍（ASD）儿童（8-18 岁），识别计算机化工作记忆（WM）训练后治疗前后潜在的改善标志物。参与者包括 26 名患有 ASD 的儿童和 18 名患有 ASD 和脆性 X 综合征（ASD+FXS）共病的儿童。分析针对年龄和智商进行了调整。与 ASD+FXS 组相比，ASD 组在 WM 训练上的改善更为显著。参与者在 WM 和远迁移结果上均有所改善，但除了重复性行为外，改善程度没有显著的组间差异。较高的多动/冲动评分预测视空间 WM 表现较差。研究结果表明认知训练可能对 ASD 和 ID 青少年有益，值得进一步探索。
