Felmlee J P, Ehman R L
Radiology. 1987 Aug;164(2):559-64. doi: 10.1148/radiology.164.2.3602402.
In clinical magnetic resonance (MR) imaging, the diagnostic quality of examinations is often degraded by streaklike flow artifacts that obscure anatomic details and reduce contrast. In addition, vascular structures are often not depicted clearly because the desired flow voids are obliterated by spurious intraluminal signals. On the basis of analysis of the physical mechanism of flow artifact formation, the authors developed a new technique for suppressing these artifacts. This applies interleaved, spectrally shaped radio frequency pulses to selectively saturate spins located in regions outside the image volume. In phantom, volunteer, and clinical imaging studies, the technique has proved to be effective by yielding a striking reduction in flow artifacts and markedly improving the reliability with which arterial and venous structures are imaged. The method has few drawbacks: It is applicable to most MR pulse sequences and, in principle, can be implemented on most imagers. It is particularly helpful for high-resolution surface coil studies of the neck, mediastinal imaging, gated cardiac imaging, and for detecting thrombus and other intravascular lesions such as dissections.
在临床磁共振（MR）成像中，检查的诊断质量常常因条纹状血流伪影而降低，这些伪影会模糊解剖细节并降低对比度。此外，血管结构常常显示不清，因为期望的血流空洞被腔内虚假信号所掩盖。基于对血流伪影形成物理机制的分析，作者开发了一种抑制这些伪影的新技术。该技术应用交错的、频谱成形的射频脉冲来选择性地饱和位于图像容积之外区域的自旋。在体模、志愿者和临床成像研究中，该技术已被证明是有效的，可显著减少血流伪影，并显著提高动脉和静脉结构成像的可靠性。该方法缺点较少：它适用于大多数MR脉冲序列，原则上可在大多数成像仪上实现。它对颈部的高分辨率表面线圈研究、纵隔成像、门控心脏成像以及检测血栓和其他血管内病变（如夹层）特别有帮助。
