Campus Centro-Oeste Dona Lindu, Federal University of São João Del-Rei, Divinópolis, Minas Gerais State, Brazil.
Centro de Pesquisa René Rachou - Fiocruz/MG, Laboratório de Química de Produtos NaturaisBelo Horizonte, Minas Gerais State, Brazil.
Nat Prod Res. 2023 Jun;37(12):2070-2075. doi: 10.1080/14786419.2022.2116702. Epub 2022 Aug 26.
(L.), popularly known as ipê-mirim, is used in traditional medicine for the treatment of diabetes and digestive problems. The components of the hexane (HE) and methanol (ME) extracts obtained from the pericarp of . were identified by gas chromatography-mass spectrometry (GC-MS) in their methyl ester forms (FAME). The antioxidant and cytotoxic activities of extracts, fatty acids, and methyl esters were evaluated. Methyl linolenate, methyl linoleate, and methyl palmitate were the major compounds in the HE, while methyl hexacosanoate was the main component in the ME. The samples exhibited significant antioxidant potential by DPPH assay. In the larvae bioassay, FAME (HE) and FAME (ME) were considered toxic. This study showed, for the first time to our knowledge, the chemical composition of the hexane and methanol extracts from pericarp, as well as the antioxidant and cytotoxic activities of the extracts, fatty acids, and methyl esters.
(L.)，俗称 ipê-mirim，在传统医学中用于治疗糖尿病和消化问题。通过气相色谱-质谱联用仪（GC-MS）以甲酯形式鉴定了从. 的果皮中获得的正己烷（HE）和甲醇（ME）提取物的成分。评估了提取物、脂肪酸和甲酯的抗氧化和细胞毒性活性。在 HE 中，甲基亚油酸酯、甲基亚麻酸酯和甲基棕榈酸酯是主要成分，而 ME 中的主要成分是甲基二十六烷酸酯。样品通过 DPPH 测定显示出显著的抗氧化潜力。在. 幼虫生物测定中，甲酯（HE）和甲酯（ME）被认为是有毒的。本研究首次表明，我们从. 的果皮中提取的正己烷和甲醇提取物的化学成分，以及提取物、脂肪酸和甲酯的抗氧化和细胞毒性活性。
