Florén C H, Benoni C, Willén R
Scand J Gastroenterol. 1987 May;22(4):459-62. doi: 10.3109/00365528708991491.
A comparison between histologic and colonoscopic extension of ulcerative colitis was made in 107 examinations (83 patients). During colonoscopy signs of inflammation were registered, and biopsy specimens were taken from the following gut segments: rectum, left colon, transverse colon, and right colon. Inflammatory activity in the specimens was graded in accordance with severity in a scale from one to five. Endoscopically, total colitis was seen in 40 examinations but was present in 70 examinations histologically. In 34 of 107 examinations the extension of disease was underestimated at colonoscopy. A slight inflammation existed in those segments that appeared normal colonoscopically. Our conclusion is that the extension of ulcerative colitis often is underestimated endoscopically and that inflammatory activity can be present in mucosa assessed as normal on colonoscopy.
对107例检查（83例患者）的溃疡性结肠炎组织学和结肠镜检查扩展情况进行了比较。结肠镜检查时记录炎症体征，并从以下肠道节段采集活检标本：直肠、左半结肠、横结肠和右半结肠。标本中的炎症活动根据严重程度分为1至5级。内镜检查时，40例检查可见全结肠炎，但组织学检查中有70例存在全结肠炎。在107例检查中的34例中，结肠镜检查时疾病的扩展被低估。在结肠镜检查显示正常的节段存在轻微炎症。我们的结论是，溃疡性结肠炎的扩展在结肠镜检查时常常被低估，并且在结肠镜检查评估为正常的黏膜中可能存在炎症活动。
