Du Ying-Chun, Li Yi-Zhen, Qin Li, Bi Hong-Yan
CAS Key Laboratory of Behavioral Science, Center for Brain Science and Learning Difficulties, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing 100049, China.
CAS Key Laboratory of Behavioral Science, Center for Brain Science and Learning Difficulties, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing 100049, China.
Brain Lang. 2022 Oct;233:105175. doi: 10.1016/j.bandl.2022.105175. Epub 2022 Aug 24.
Dyslexic readers have been reported to show abnormal temporal acuity and multisensory integration deficiency. Here, we investigated the influence of temporal intervals on Chinese character-speech integration in children with and without dyslexia. Visual characters were presented synchronously to the onset of speech sounds (AV0) or before speech sound by 300 ms (AV300). Event-related potentials (ERP) evoked by congruent condition (speech sounds presented with congruent Chinese characters) and by baseline condition (speech sounds presented with Korean characters) were compared. Typically developing (TD) children exhibited congruency effect in AV0 condition, whereas dyslexic children exhibited congruency effect in AV300 condition. Moreover, congruency effect in TD children was due to enhanced neural activation to congruent trials, congruency effect in dyslexic children was contributed by neural suppression for baseline trials. These results suggested that different underlying mechanisms were involved in character-speech integration for typical and dyslexic children.
据报道，阅读障碍患者表现出异常的时间敏锐度和多感官整合缺陷。在此，我们研究了时间间隔对有阅读障碍和无阅读障碍儿童汉字-语音整合的影响。视觉汉字与语音的起始同步呈现（AV0）或在语音前300毫秒呈现（AV300）。比较了由一致条件（语音与一致的汉字同时呈现）和基线条件（语音与韩文字符同时呈现）诱发的事件相关电位（ERP）。发育正常（TD）的儿童在AV0条件下表现出一致性效应，而阅读障碍儿童在AV300条件下表现出一致性效应。此外，TD儿童的一致性效应是由于对一致试验的神经激活增强，阅读障碍儿童的一致性效应是由对基线试验的神经抑制所致。这些结果表明，典型儿童和阅读障碍儿童在汉字-语音整合中涉及不同的潜在机制。
