Shi Z Y, Gu Z Z, Li C M
Sci Sin B. 1986 Dec;29(12):1303-15.
The present investigation was made in rabbits and cats with perfusing mock cerebrospinal fluid into fourth ventriculus to produce experimental diffusion intracranial hypertension. Under normoxia and acute hypoxia conditions, the changes in cerebral blood flow, spontaneous electrocortical activity, direct cortical response, electrocardiogram, blood pressure and cerebral perfusion pressure were measured as intracranial hypertension caused by step elevation and abrupt elevation; at the same time, the relationship mentioned above was also investigated. The experimental results are very important to clinic treatment and to the patients suffering from anoxia with intracranial hypertension.
本研究在兔和猫身上进行，通过向第四脑室灌注模拟脑脊液以产生实验性弥漫性颅内高压。在常氧和急性缺氧条件下，测量了因颅内压逐步升高和突然升高所导致的颅内高压状态下的脑血流量、自发皮质电活动、直接皮质反应、心电图、血压和脑灌注压的变化；同时，也研究了上述各指标之间的关系。实验结果对于临床治疗以及患有颅内高压缺氧的患者具有重要意义。
