Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 W Drake Rd., Fort Collins, CO 80525, USA.
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 W Drake Rd., Fort Collins, CO 80525, USA.
J Vet Cardiol. 2022 Oct;43:61-69. doi: 10.1016/j.jvc.2022.07.003. Epub 2022 Aug 1.
Congenital membranous ventricular septal aneurysm has been reported in dogs and can be associated with a perimembranous ventricular septal defect (VSD). The windsock-like ventricular septal aneurysm is formed by tissue of the membranous ventricular septum and portions of the septal leaflet of the tricuspid valve. We report two dogs that underwent transcatheter closure of perimembranous VSD associated with membranous ventricular septal aneurysm using a commercial device marketed for transcatheter closure of patent ductus arteriosus, the canine duct occluder. Partial closure was achieved in the first dog with reduction in left heart dimensions documented on echocardiography both at one day and nine months after procedure. In the second dog, three-dimensional transesophageal echocardiography, cardiac computed tomography, and a three-dimensionally printed whole heart model were used to evaluate feasibility for transcatheter device closure. Complete closure of the VSD was subsequently achieved. Both cases had good short- to medium-term outcomes, no perioperative complications were observed, and both dogs are apparently healthy and receiving no cardiac medications at 34 months and 17 months after procedure. Transcatheter attenuation of perimembranous VSD with membranous ventricular septal aneurysm is clinically feasible using the canine duct occluder, and multimodal cardiac imaging allows accurate assessment and planning prior to transcatheter intervention for structural heart disease in dogs.
先天性膜性室间隔瘤已在犬中报道，并可与膜周室间隔缺损（VSD）相关。风箱样室间隔瘤由膜性室间隔组织和三尖瓣隔瓣的部分组成。我们报告了两例使用一种商业器械经导管闭合伴膜性室间隔瘤的膜周 VSD 的犬，该器械是一种用于经导管闭合动脉导管未闭的器械，即犬动脉导管塞。第一只犬在术后一天和九个月时经超声心动图证实左心尺寸减小，实现了部分闭合。在第二只犬中，使用三维经食管超声心动图、心脏计算机断层扫描和三维打印的整个心脏模型来评估经导管器械闭合的可行性。随后成功地完全闭合了 VSD。这两个病例都有良好的短期至中期结果，没有观察到围手术期并发症，并且在术后 34 个月和 17 个月，这两只犬显然都很健康，没有服用心脏药物。使用犬动脉导管塞经导管衰减伴膜性室间隔瘤的膜周 VSD 在临床上是可行的，多模态心脏成像允许在经导管介入治疗犬的结构性心脏病之前进行准确的评估和计划。
