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药品专利池与全球药品扩散和创新。

Global drug diffusion and innovation with the medicines patent pool.

机构信息

University of Massachusetts Amherst, Amherst, MA, United States; Max Planck Institute for Innovation and Competition, Munich, Germany; Canadian Centre for Health Economics, University of Toronto, Canada.

出版信息

J Health Econ. 2022 Sep;85:102671. doi: 10.1016/j.jhealeco.2022.102671. Epub 2022 Aug 14.

Abstract

This paper studies the impact of the first joint licensing platform for patented drugs, the Medicines Patent Pool, on global drug diffusion and innovation. The pool allows generic firms worldwide to license drug bundles cheaply and conveniently for sales in a set of developing countries. I construct a novel dataset from licensing contracts, public procurement, clinical trials, and drug approvals. Using difference-in-differences methods, I find that the pool leads to substantial increases in the generic supply of drugs purchased, particularly in countries with stronger patent protection. In addition, there are some positive increases in clinical trials and drug product approvals after a compound enters the pool, mostly by firms outside the pool.

摘要

本文研究了第一个专利药品联合许可平台——药品专利池对全球药品扩散和创新的影响。该平台允许全球的仿制药公司以低廉且便捷的方式获得药品包的许可,以便在一系列发展中国家销售。我从许可合同、公共采购、临床试验和药品批准等方面构建了一个新颖的数据集。使用双重差分法,我发现该平台显著增加了购买的仿制药供应,特别是在专利保护较强的国家。此外,在一种化合物进入该平台后,临床试验和药品批准也出现了一些积极的增加,主要是由平台外的公司推动的。

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