Centre of Genomics and Policy (CGP), McGill University, Montreal, Québec, Canada.
Centre of Genomics and Policy (CGP), McGill University, Montreal, Québec, Canada.
Crit Rev Oncol Hematol. 2022 Oct;178:103797. doi: 10.1016/j.critrevonc.2022.103797. Epub 2022 Aug 27.
Health professionals not specialized in genetics are expected to take an increasing role in genetic services delivery. This article aims to identify legal and ethical challenges related to a collaborative oncogenetics service model, where non-genetic health professionals provide genetic services to patients. Through a scoping literature review, we identified issues to the provision of hereditary breast and ovarian cancer, or other hereditary adult cancers, genetic testing under this model. Concerns that arose in the literature were informed consent, lack of adherence to best practice guidelines, lack of education of non-genetic health professionals on the provision of genetic services, psychological impacts of genetic testing, continuity of care, the complexity of genetic test results, confidentiality, risks of medical mismanagement, and the associated medical responsibility liabilities. Despite these challenges, there is a growing consensus towards the feasibility of cancer genetic testing being undertaken by non-genetic healthcare professionals in a collaborative oncogenetics service model.
预计非遗传专业的健康专业人员将在遗传服务提供中发挥越来越重要的作用。本文旨在确定与协作肿瘤遗传学服务模式相关的法律和伦理挑战，在该模式下，非遗传健康专业人员为患者提供遗传服务。通过范围广泛的文献回顾，我们确定了在该模型下提供遗传性乳腺癌和卵巢癌或其他遗传性成人癌症遗传检测的问题。文献中提出的问题包括知情同意、不遵守最佳实践指南、非遗传健康专业人员在提供遗传服务方面缺乏教育、遗传检测的心理影响、护理连续性、遗传检测结果的复杂性、保密性、医疗管理失误的风险以及相关的医疗责任责任。尽管存在这些挑战，但越来越多的人认为，在协作肿瘤遗传学服务模式中，非遗传医疗保健专业人员进行癌症基因检测是可行的。
