Falkson Conrad B, Vella Emily T, Ellis Peter M, Maziak Donna E, Ung Yee C, Yu Edward
Radiation Oncology, Cancer Centre of Southeastern Ontario, Kingston General Hospital and Queen's University, Kingston, Ontario, Canada.
Program in Evidence-Based Care, Cancer Care Ontario, McMaster University, Hamilton, Ontario, Canada.
J Thorac Oncol. 2022 Nov;17(11):1258-1275. doi: 10.1016/j.jtho.2022.08.007. Epub 2022 Aug 27.
The aim of this guideline was to provide recommendations for the most effective therapy for patients with thymic epithelial tumors, including thymoma, thymic carcinoma, and thymic neuroendocrine tumors (NETs). This guideline is intended to be used by all health care professionals managing patients with thymic epithelial tumors.
The guideline was developed by Ontario Health (Cancer Care Ontario)'s Program in Evidence-Based Care and by the Lung Cancer Disease Site Group through a systematic review of the evidence, expert consensus, and formal internal and external reviews.
Evidence-based recommendations were developed to improve the management of patients with thymic epithelial tumors. The guideline includes recommendations for surgical, radiation, and systemic treatments for patients with thymoma, thymic carcinoma, and thymic NETs separated by stage of disease using the TNM staging system. Recommendations for patients with thymic NETs were endorsed from the 2021 National Comprehensive Cancer Network Neuroendocrine and Adrenal Tumors Guideline.
This guideline reflects the new staging system for patients with thymoma and thymic carcinoma and includes supporting evidence from the best available studies.
本指南的目的是为胸腺瘤、胸腺癌和胸腺神经内分泌肿瘤（NETs）等胸腺上皮肿瘤患者提供最有效治疗的建议。本指南供所有管理胸腺上皮肿瘤患者的医疗保健专业人员使用。
本指南由安大略省卫生厅（安大略癌症护理中心）基于证据的护理项目以及肺癌疾病部位小组通过对证据进行系统回顾、专家共识以及正式的内部和外部审查而制定。
制定了基于证据的建议以改善胸腺上皮肿瘤患者的管理。该指南包括使用TNM分期系统按疾病阶段对胸腺瘤、胸腺癌和胸腺NETs患者进行手术、放疗和全身治疗的建议。胸腺NETs患者的建议来自2021年国家综合癌症网络神经内分泌和肾上腺肿瘤指南。
本指南反映了胸腺瘤和胸腺癌患者的新分期系统，并包括现有最佳研究的支持证据。
