Clinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, 481875School of Medicinee, Tongji University, Shanghai, China.
School of Medicine, Tongji University, Shanghai, China.
J Appl Gerontol. 2022 Dec;41(12):2490-2498. doi: 10.1177/07334648221118352. Epub 2022 Aug 28.
We aimed to examine the longitudinal association between frailty and cognitive impairment in the older Chinese population. This prospective cohort study used data from the Chinese Longitudinal Healthy Longevity Study 2011 wave. We calculated the follow-up duration as 3 years from the baseline year. Frailty was measured using the frailty index, and cognitive function was calculated by Mini-Mental State Examination Scale. Participants who were non-frailty and those with normal cognitive function were included in 2011 and followed up in 2014, respectively. Frailty was an independent risk factor for early-onset cognitive impairment. Age, hearing impairment, and a decreased ability to perform daily activities were the main risk factors for cognitive impairment, while affluent economic status was a protective factor. Cognitive impairment was not found to be an independent risk factor for frailty. We concluded that the frailty index is a significant predictor of cognitive impairment among community-dwelling older adults.
我们旨在探讨中国老年人群中衰弱与认知障碍的纵向关联。这项前瞻性队列研究使用了中国健康长寿纵向研究 2011 年波的数据。我们将随访时间从基线年计算为 3 年。使用衰弱指数来衡量衰弱，使用简易精神状态检查量表来计算认知功能。2011 年被纳入非衰弱且认知功能正常的参与者，并在 2014 年进行了随访。衰弱是认知障碍早期发病的独立危险因素。年龄、听力障碍和日常活动能力下降是认知障碍的主要危险因素，而富裕的经济状况是保护因素。认知障碍不是衰弱的独立危险因素。我们的结论是，衰弱指数是社区居住的老年人认知障碍的重要预测指标。
