Special issue: informatics & data-driven medicine-2021.

Modern medical diagnosis, treatment, or rehabilitation problems of the patient reach completely different levels due to the rapid development of artificial intelligence tools. Methods of machine learning and optimization based on the intersection of historical data of various volumes provide significant support to physicians in the form of accurate and fast solutions of automated diagnostic systems. It significantly improves the quality of medical services. This special issue deals with the problems of medical diagnosis and prognosis in the case of short datasets. The problem is not new, but existing machine learning methods do not always demonstrate the adequacy of prediction or classification models, especially in the case of limited data to implement the training procedures. That is why the improvement of existing and development of new artificial intelligence tools that will be able to solve it effectively is an urgent task. The special issue contains the latest achievements in medical diagnostics based on the processing of small numerical and image-based datasets. Described methods have a strong theoretical basis, and numerous experimental studies confirm the high efficiency of their application in various applied fields of Medicine.