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基于图的结构知识感知网络用于辅助诊断。

Graph-based structural knowledge-aware network for diagnosis assistant.

机构信息

School of Computer and Artificial Intelligence, Zhengzhou University, Zhengzhou, China.

Pengcheng Laboratory, Shenzhen, China.

出版信息

Math Biosci Eng. 2022 Jul 25;19(10):10533-10549. doi: 10.3934/mbe.2022492.

Abstract

Diagnosis assistant is an effective way to reduce the workloads of professional doctors. The rich professional knowledge plays a crucial role in diagnosis. Therefore, it is important to introduce the relevant medical knowledge into diagnosis assistant. In this paper, diagnosis assistant is treated as a classification task, and a Graph-based Structural Knowledge-aware Network (GSKN) model is proposed to fuse Electronic Medical Records (EMRs) and medical knowledge graph. Considering that different information in EMRs affects the diagnosis results differently, the information in EMRs is categorized into general information, key information and numerical information, and is introduced to GSKN by adding an enhancement layer to the Bidirectional Encoder Representation from Transformers (BERT) model. The entities in EMRs are recognized, and Graph Convolutional Neural Networks (GCN) is employed to learn deep-level graph structure information and dynamic representation of these entities in the subgraphs. An interactive attention mechanism is utilized to fuse the enhanced textual representation and the deep representation of these subgraphs. Experimental results on Chinese Obstetric Electronic Medical Records (COEMRs) and open dataset C-EMRs demonstrate the effectiveness of our model.

摘要

诊断辅助是一种有效减轻专业医生工作量的方法。丰富的专业知识在诊断中起着至关重要的作用。因此,将相关医学知识引入诊断辅助中非常重要。本文将诊断辅助视为分类任务,并提出了一种基于图的结构知识感知网络(GSKN)模型,用于融合电子病历(EMR)和医学知识图。考虑到 EMR 中的不同信息对诊断结果的影响不同,将 EMR 中的信息分为一般信息、关键信息和数值信息,并通过在 Transformer 模型的双向编码器表示(BERT)中添加增强层将信息引入 GSKN。识别 EMR 中的实体,并利用图卷积神经网络(GCN)学习子图中这些实体的深层图结构信息和动态表示。利用交互注意力机制融合增强后的文本表示和这些子图的深层表示。在中文妇产科电子病历(COEMRs)和公开数据集 C-EMRs 上的实验结果表明了我们模型的有效性。

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