Kim Mirae, Hyun Sang-Hwan
Laboratory of Veterinary Embryology and Biotechnology, Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, South Korea.
Institute of Stem Cell and Regenerative Medicine, Chungbuk National University, Cheongju, South Korea.
Front Vet Sci. 2022 Aug 10;9:931402. doi: 10.3389/fvets.2022.931402. eCollection 2022.
Pigs are cost-effective industrial animals because they produce a large number of offspring and have shorter rebreeding intervals compared with other animals, such as non-human primates. The reproductive physiology of pigs has been studied over the past several decades. However, there is not enough research on the effects of the neurotrophic factors on the ovarian physiology and development in pigs. As the ovary is a highly innervated organ, various neurotrophic factors during ovarian development can promote the growth of nerve fibers and improve the development of ovarian cells. Thus, investigating the role of neurotrophic factors on ovarian development, and the relationship between neurotrophic factors and porcine female reproduction is worth studying. In this review, we focused on the physiological roles of various neurotrophic factors in porcine ovaries and summarized the current status of the studies related to the relationship between neurotrophic factors and porcine ovarian development.
猪是具有成本效益的养殖动物，因为与其他动物（如非人灵长类动物）相比，它们能产下大量后代，且再繁殖间隔更短。在过去几十年里，猪的生殖生理学已得到研究。然而，关于神经营养因子对猪卵巢生理学和发育的影响，目前尚无足够的研究。由于卵巢是一个神经高度密集的器官，卵巢发育过程中的各种神经营养因子可促进神经纤维的生长，并改善卵巢细胞的发育。因此，研究神经营养因子在卵巢发育中的作用以及神经营养因子与猪雌性生殖之间的关系是值得的。在这篇综述中，我们重点关注了各种神经营养因子在猪卵巢中的生理作用，并总结了神经营养因子与猪卵巢发育关系的研究现状。
