Knowles Kurt J, Avalos Sara R, Shi Mingxia, Parwani Anil, Holloway Alec R, Keel Christopher E
Department of Pathology, 2451 University Hospital Drive, University of South Alabama, Mobile, AL, 36617, USA.
Department of Pathology, E409 Doan Hall, 410 West 10th Ave, Ohio State University, Columbus, OH, 43210, USA.
Urol Case Rep. 2022 Aug 3;45:102169. doi: 10.1016/j.eucr.2022.102169. eCollection 2022 Nov.
Rhabdomyosarcomas with bladder involvement in adults is an extremely rare tumor with approximately 35 cases reported. Because of its rarity in adults the exact treatment modalities are not entirely clear. Treatment is based on Children's Oncology Group in RMS. There is no significant difference in stage, lymph node status, gender, and site between adults and children. The 5 year survival for pediatric RMS is 66% and for adults 22%. It is clear that our understanding and treatment of pediatric RMS is much greater than that of adult patients and the possible reason for these differences are discussed.
成人膀胱受累的横纹肌肉瘤是一种极为罕见的肿瘤，据报道约有35例。由于其在成人中罕见，确切的治疗方式并不完全明确。治疗基于儿童肿瘤学组关于横纹肌肉瘤的方案。成人和儿童在分期、淋巴结状态、性别和部位方面没有显著差异。儿童横纹肌肉瘤的5年生存率为66%，成人为22%。显然，我们对儿童横纹肌肉瘤的理解和治疗比对成人患者的了解要多得多，并且讨论了这些差异可能的原因。
