Mortazavi Matin, Aigner Kiera, Antono Jessica E, Gambacorta Christina, Nahum Mor, Levi Dennis M, Föcker Julia
Department of Radiology, University Hospital LMU, Nussbaumstr. 7, 80336 Munich, Germany.
Department of Psychiatry and Psychotherapy, University Hospital LMU, Nussbaumstr. 7, 80336 Munich, Germany.
iScience. 2022 Aug 5;25(9):104871. doi: 10.1016/j.isci.2022.104871. eCollection 2022 Sep 16.
Early blindness results in alterations in the neural responses to auditory stimuli. Here we show that even moderately reduced vision in one eye early in life is sufficient to induce neural plastic changes in voice processing. We asked individuals with reduced visual acuity in one eye due to amblyopia to attend to vocal cues during electroencephalogram recording. We found enhanced frontal auditory responses at 125 ms-225 ms, which were correlated with reduced vision in the amblyopic eye, but not the fellow eye. Our results indicate intramodal reorganization, typically observed after congenital profound visual deprivation.
早期失明会导致对听觉刺激的神经反应发生改变。在此我们表明，即使在生命早期一只眼睛的视力有适度下降，也足以在语音处理过程中诱发神经可塑性变化。我们让因弱视导致一只眼睛视力下降的个体在脑电图记录期间关注声音线索。我们发现在125毫秒至225毫秒时额叶听觉反应增强，这与弱视眼而非另一只眼睛的视力下降相关。我们的结果表明存在模式内重组，这种重组通常在先天性严重视觉剥夺后观察到。
