Editorial: Kappa opioid receptors revealed: Disentangling the pharmacology to open up new therapeutic strategies.
作者信息
Walwyn Wendy Margaret, Valenza Marta
机构信息
Jane & Terry Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, United States.
Department of Physiology and Pharmacology "Vittorio Erspamer", Sapienza University of Rome, Rome, Italy.
出版信息
Front Pharmacol. 2022 Aug 12;13:973780. doi: 10.3389/fphar.2022.973780. eCollection 2022.
Abstract
摘要
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本文引用的文献
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Sigma receptor-induced heavy drinking in rats: Modulation by the opioid receptor system.Sigma 受体诱导大鼠过度饮酒：阿片受体系统的调制。
Pharmacol Biochem Behav. 2020 May;192:172914. doi: 10.1016/j.pbb.2020.172914. Epub 2020 Mar 20.
2
Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat.选择性短效拮抗剂盐酸LY2444296对κ阿片受体的阻断在大鼠慢性延长可卡因自我给药及再次接触过程中的作用。
Psychopharmacology (Berl). 2020 Apr;237(4):1147-1160. doi: 10.1007/s00213-019-05444-4. Epub 2020 Jan 8.
3
Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain.κ 阿片受体驱动慢性疼痛的持续厌恶成分。
J Neurosci. 2019 May 22;39(21):4162-4178. doi: 10.1523/JNEUROSCI.0274-19.2019. Epub 2019 Mar 12.
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Untangling the complexity of opioid receptor function.解析阿片受体功能的复杂性。
Neuropsychopharmacology. 2018 Dec;43(13):2514-2520. doi: 10.1038/s41386-018-0225-3. Epub 2018 Sep 24.
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Dynorphin/kappa-opioid receptor control of dopamine dynamics: Implications for negative affective states and psychiatric disorders.脑啡肽/κ-阿片受体对多巴胺动态的控制：对负性情绪状态和精神障碍的影响。
Brain Res. 2019 Jun 15;1713:91-101. doi: 10.1016/j.brainres.2018.09.023. Epub 2018 Sep 19.
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Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders.阿片 κ 受体拮抗剂 CERC-501 治疗酒精使用障碍的临床前评估。
Neuropsychopharmacology. 2018 Aug;43(9):1805-1812. doi: 10.1038/s41386-018-0015-y. Epub 2018 Feb 5.
7
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Psychopharmacology (Berl). 2017 Aug;234(15):2219-2231. doi: 10.1007/s00213-017-4647-0. Epub 2017 May 27.
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Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials.用于精神疾病的κ-阿片受体拮抗剂：从实验室到临床试验
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