生物关节修复：转化研究的成功案例。
Biologic Joint Restoration: A Translational Research Success Story.
机构信息
William and Kathryn Allen Distinguished Chair in Orthopaedic Surgery; Director, Thompson Laboratory for Regenerative Orthopaedics (TLRO) and Mizzou BioJoint® Center; and Vice Chair, Orthopaedic Research Division, University of Missouri - Columbia, Columbia, Missouri.
TLRO and Department of Orthopaedic Surgery (DOS), University of Missouri - Columbia, Columbia, Missouri.
出版信息
Mo Med. 2022 Mar-Apr;119(2):115-121.
Abstract
Treatment options that result in consistently successful outcomes for young and active patients with joint disorders are needed. This article summarizes two decades of rigorous research using a bedside-to-bench- to-bedside translational approach based on the One Health - One Medicine concept that culminated in successful clinical use of biologic joint restoration options for treatment of knee, hip, ankle, and shoulder problems in this growing patient population.
摘要
需要为患有关节疾病的年轻且活跃的患者提供始终能取得成功结果的治疗选择。本文总结了二十年来使用基于“同一健康-同一医学”理念的床边到床边再到床边的转化研究方法进行的严格研究，最终成功将生物关节修复作为治疗这类不断增长的患者群体的膝关节、髋关节、踝关节和肩关节问题的选择。
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本文引用的文献
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Outcomes Associated With Osteochondral Allograft Transplantation in Dogs.犬同种异体骨软骨移植的相关结果
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Revision Total Knee Arthroplasty in Young Patients: Higher Early Reoperation and Rerevision.年轻患者的全膝关节翻修术：更高的早期再手术和再次翻修率。
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Unicompartmental bipolar osteochondral and meniscal allograft transplantation is effective for treatment of medial compartment gonarthrosis in a canine model.单髁双极骨软骨和半月板同种异体移植治疗犬膝关节内侧间室骨关节炎模型有效。
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Patient-Reported Outcomes for Large Bipolar Osteochondral Allograft Transplantation in Combination with Realignment Osteotomies for the Knee.患者报告的大型双相骨软骨同种异体移植联合膝关节再排列截骨术的结果。
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Comparison of meniscal allograft transplantation techniques using a preclinical canine model.使用临床前犬模型比较半月板同种异体移植技术。
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