Wang Wenjing, Huangfu Hui, Hou Yanjie, Feng Yan, Zhang Chunming, Zhai Songyu, Li Menglu
First Clinical Medical College of Shanxi Medical University,Taiyuan,030000,China.
Department of Otorhinolaryngology Head and Neck Surgery,First Hospital of Shanxi Medical University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Sep;36(9):721-725. doi: 10.13201/j.issn.2096-7993.2022.09.015.
Laryngeal cancer is one of the most common malignant cancer of the head and neck. Concurrent chemoradiotherapy is considered by the NCCN guideline to be the most effective organ protection strategy for locally advanced laryngeal cancer, which can preserve the larynx without reducing the survival rate of patients. Patients with non-T4 (T1-3) and high lymph node burden (N2-3) laryngeal cancer can benefit from concurrent chemoradiotherapy, which are more suitable for concurrent chemoradiotherapy than locally advanced laryngeal cancer with other stages. The indications of concurrent chemoradiotherapy were further discussed in this paper.
喉癌是头颈部最常见的恶性肿瘤之一。美国国立综合癌症网络(NCCN)指南认为,同步放化疗是局部晚期喉癌最有效的器官保护策略,可在不降低患者生存率的情况下保留喉部。非T4期(T1-3)且淋巴结负荷高(N2-3)的喉癌患者可从同步放化疗中获益,相较于其他分期的局部晚期喉癌,这类患者更适合同步放化疗。本文进一步探讨了同步放化疗的适应证。