Klinkova A S, Kamenskaya O V, Loginova I Y, Porotnikova S S, Lomivorotov V N, Chernyavskiy A M, Lomivorotov V V
Meshalkin National Medical Research Center, Novosibirsk, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(8):80-87. doi: 10.17116/jnevro202212208180.
To study the features of the psychoemotional status in patients with chronic thromboembolic pulmonary hypertension in the long term after pulmonary thromboendarterectomy (PTE) during the COVID-19 pandemic and to identify factors affecting the development of clinically pronounced anxiety and depressive disorders.
Psychoemotional status was analyzed in 151 patients in the long term after PTE using the Generalized Anxiety Disorder (GAD) Assessment (GAD-7) and the Beck Depression Inventory. The number of patients who underwent COVID-19 was recorded and the functional status scale of the patient who underwent COVID-19 (PCFS) was evaluated. Logistic regression analysis was used to identify predictors of clinically pronounced depression and GAD in the long-term period after surgery during the COVID-19 pandemic.
Clinically significant GAD and depression in the long-term period after PTE during the COVID-19 pandemic were observed in 11 and 17.8% of patients, respectively. Clinically pronounced depression is associated with older age, chronic cerebral circulatory insufficiency and pronounced post COVID-19 disorders of functional status according to PCFS. The development of GAD symptoms is influenced by cardiopulmonary insufficiency in the hospital period after PTE. The combination of anxiety and depression symptoms is correlated with older age.
In patients in the long term after PTE during the COVID-19 pandemic, the symptoms of GAD and depression were detected in 11 and 17.8% of cases, respectively. The complicated course of cardiac surgery has shown a negative impact on the development of GAD in the long term after surgery. The factors influencing the development of clinically pronounced depression were older age, chronic cerebral circulatory insufficiency and pronounced post COVID-19 disorders of functional status.
研究在新冠疫情期间，慢性血栓栓塞性肺动脉高压患者接受肺动脉血栓内膜剥脱术（PTE）后的长期心理情绪状态特征，并确定影响临床显著焦虑和抑郁障碍发生的因素。
使用广泛性焦虑障碍评估量表（GAD-7）和贝克抑郁量表，对151例PTE术后患者的长期心理情绪状态进行分析。记录感染新冠病毒的患者数量，并评估感染新冠病毒患者的功能状态量表（PCFS）。采用逻辑回归分析确定新冠疫情期间手术后长期临床显著抑郁和广泛性焦虑障碍的预测因素。
在新冠疫情期间，PTE术后长期出现临床显著广泛性焦虑障碍和抑郁的患者分别占11%和17.8%。根据PCFS，临床显著抑郁与年龄较大、慢性脑循环功能不全以及新冠感染后明显的功能状态障碍有关。广泛性焦虑障碍症状的出现受PTE术后住院期间心肺功能不全的影响。焦虑和抑郁症状的组合与年龄较大相关。
在新冠疫情期间，PTE术后长期患者中，分别有11%和17.8%的病例出现广泛性焦虑障碍和抑郁症状。心脏手术的复杂过程对术后长期广泛性焦虑障碍的发生产生了负面影响。影响临床显著抑郁发生的因素包括年龄较大、慢性脑循环功能不全以及新冠感染后明显的功能状态障碍。
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