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认知障碍中的药物治疗及其对口腔健康的影响。

Drug Therapy in Cognitive Disorders and Its Effects on Oral Health.

作者信息

Ahmed Syed Ershad, Begum Rizwana, Kumar Aparna S, M Arun, R Vaishnavi, I Vinith

机构信息

Prosthodontics, Sri Ramakrishna Dental College and Hospital, Coimbatore, IND.

Oral Medicine, Vinayaka Missions Research Foundation (VMRF) Deemed to be University, Salem, IND.

出版信息

Cureus. 2022 Jul 24;14(7):e27194. doi: 10.7759/cureus.27194. eCollection 2022 Jul.

Abstract

Dementia and Alzheimer's disease are the two most characteristic cognitive disorders presenting numerous cognitive dysfunctions such as memory loss, functional impairment, speech impairment, and orientation problems. In India, there is an increased risk in the elderly population leading to the prevalence of Alzheimer's and dementia-related diseases. Therefore, it is not only general health care practitioners but also oral health care providers also play a major role in rehabilitating and treating this type of patient. So, it is necessary for oral health care providers to understand the pharmacologic agents used for the management of Alzheimer's and dementia-related diseases. This article gives an insight into the management of dementia and Alzheimer's disease and also an update on the drug therapies for AD and outlines their implications on oral health.

摘要

痴呆症和阿尔茨海默病是两种最典型的认知障碍,表现出许多认知功能障碍,如记忆力丧失、功能损害、言语障碍和定向障碍。在印度,老年人口患病风险增加,导致阿尔茨海默病和痴呆症相关疾病的流行。因此,不仅普通医疗保健从业者,口腔保健提供者在这类患者的康复和治疗中也发挥着重要作用。所以,口腔保健提供者有必要了解用于治疗阿尔茨海默病和痴呆症相关疾病的药物。本文深入探讨了痴呆症和阿尔茨海默病的治疗方法,以及阿尔茨海默病药物治疗的最新情况,并概述了它们对口腔健康的影响。

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本文引用的文献

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Clinical trials of new drugs for Alzheimer disease.治疗阿尔茨海默病新药的临床试验。
J Biomed Sci. 2020 Jan 6;27(1):18. doi: 10.1186/s12929-019-0609-7.
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The dementia epidemic: Impact, prevention, and challenges for India.痴呆症流行:对印度的影响、预防及挑战
Indian J Psychiatry. 2018 Apr-Jun;60(2):165-167. doi: 10.4103/psychiatry.IndianJPsychiatry_261_18.
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Association between mastication and cognitive status: A systematic review.咀嚼与认知状态之间的关联:一项系统综述。
Arch Gerontol Geriatr. 2017 May-Jun;70:44-53. doi: 10.1016/j.archger.2016.12.006. Epub 2016 Dec 14.
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Correlation of cognitive and masticatory function in Alzheimer's disease.阿尔茨海默病中认知功能与咀嚼功能的相关性
Clin Oral Investig. 2017 Mar;21(2):573-578. doi: 10.1007/s00784-016-1923-z. Epub 2016 Jul 30.

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