Herd R P, Reinemeyer C R, Heider L E
Vet Rec. 1987 Apr 25;120(17):406-9. doi: 10.1136/vr.120.17.406.
Dairy replacement heifers given two strategic treatments with ivermectin (0.2 mg/kg) three and eight weeks after turnout to spring pastures in northern USA had mean adjusted weight gains (62.3 kg) that were 62 per cent (P less than 0.02) greater than those of control heifers (38.5 kg) at the time of winter housing. Pasture infectivity was consistently higher in control pastures and there was a sixfold difference between treatment (56 L3/kg) and control (358 L3/kg) pastures by the time of winter housing on October 18. This study confirmed earlier studies in northern USA demonstrating the value of two strategic treatments in achieving significant increases in weight gains and hastening the time of first breeding by one to three months at a saving of $40 to $140 per heifer. It was concluded that this dosing strategy is a satisfactory method of parasite control for dairy replacement heifers in northern USA without undue selection for drug resistance.
在美国北部,春季牧场放牧后3周和8周时,给后备奶牛用伊维菌素(0.2毫克/千克)进行两次预防性治疗,到冬季圈养时,接受治疗的后备奶牛平均体重增加量(62.3千克)比对照奶牛(38.5千克)高62%(P<0.02)。对照牧场的牧草感染性一直较高,到10月18日冬季圈养时,治疗牧场(56个三期幼虫/千克)和对照牧场(358个三期幼虫/千克)之间相差6倍。这项研究证实了美国北部早期的研究结果,即两次预防性治疗对于显著增加体重以及将首次配种时间提前1至3个月具有重要价值,每头后备奶牛可节省40至140美元。研究得出结论,这种给药策略是美国北部后备奶牛寄生虫控制的一种令人满意的方法,不会过度选择产生耐药性。