Suppr超能文献

比较 CDHSG 模型和 PCO 在预测先天性膈疝患者死亡率风险中的作用。

Comparison of CDHSG model and PCO in predicting mortality risk in patients with congenital diaphragmatic hernia.

机构信息

Department of Pediatric Surgery, University of Health Sciences Diyarbakır Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.

出版信息

Congenit Anom (Kyoto). 2022 Nov;62(6):236-240. doi: 10.1111/cga.12491. Epub 2022 Sep 13.

Abstract

Congenital diaphragmatic hernia (CDH) is one of the illnesses with high mortality and morbidity rates. The study aims to compare the Congenital Diaphragmatic Hernia Study Group (CDHSG) model and PCO in determining the mortality risk of CDH in the early postnatal period in neonates. The data of 35 patients who were treated CDH were analyzed retrospectively. The sex, gestational age, birth weight, delivery method, presence of chromosomal anomaly, congenital cardiac and other anomalies, pulmonary hypertension, the 5-min Apgar score, PCO values of blood gas in the first 24 h, mode of ventilation were recorded. According to the CDHSG model, the mortality risk of CDH was divided into three categories: as low, moderate, high risk. Based on the blood gases in the first 24 h after delivery, the CDH mortality risk was considered in two categories as low and high. Based on the CDHSG model, the risk of CDH mortality was low in 11.4%, moderate in 20%, and high in 68.6%. Mortality rates were 0%, 42.8%, and 83.3%, respectively. Based on the PaCO , the risk of CDH mortality was low in 37.1% of patients and high in 62.8%. The mortality rate was 86.3% in high-severity patients and 30.7% in low-risk patients. No significant difference was found between the area under the curve values of the CDHSG model and PCO . Especially in developing countries, in cases where opportunities are limited, the severity of the disease, the need for more aggressive treatment, and the need for higher-level intensive care can be determined with the easily accessible and low-cost blood gas PCO at the bedside.

摘要

先天性膈疝 (CDH) 是一种死亡率和发病率都很高的疾病。本研究旨在比较先天性膈疝研究组 (CDHSG) 模型和 PCO ,以确定新生儿期 CDH 的早期死亡风险。回顾性分析了 35 例接受 CDH 治疗的患者数据。记录了性别、胎龄、出生体重、分娩方式、染色体异常、先天性心脏病和其他异常、肺动脉高压、出生后 5 分钟 Apgar 评分、第 1 至 24 小时血气 PCO 值、通气模式。根据 CDHSG 模型,CDH 的死亡风险分为低、中、高三个风险类别。根据分娩后第 1 至 24 小时的血气情况,将 CDH 死亡风险分为低危和高危两类。根据 CDHSG 模型,CDH 死亡风险低的占 11.4%,中度的占 20%,高的占 68.6%。死亡率分别为 0%、42.8%和 83.3%。根据 PaCO ,CDH 死亡风险低的患者占 37.1%,高的占 62.8%。高危患者死亡率为 86.3%,低危患者死亡率为 30.7%。CDHSG 模型和 PCO 的曲线下面积值之间无显著差异。尤其是在发展中国家,机会有限的情况下,可以通过床边易于获得且成本低廉的血气 PCO 来确定疾病的严重程度、是否需要更积极的治疗以及是否需要更高水平的重症监护。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验